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Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease

INTRODUCTION: Possession of the apolipoprotein E (APO E) ε4 allele advances amyloid β (Aβ) deposition and symptomatic onset of Alzheimer's disease (AD), whereas its effect on the rate of cognitive decline remained controversial. We examined the effects of APOE ε4 allele on cognition in biomarke...

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Detalles Bibliográficos
Autores principales:	Suzuki, Kazushi, Hirakawa, Akihiro, Ihara, Ryoko, Iwata, Atsushi, Ishii, Kenji, Ikeuchi, Takeshi, Sun, Chung‐Kai, Donohue, Michael, Iwatsubo, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087431/ https://www.ncbi.nlm.nih.gov/pubmed/32211510 http://dx.doi.org/10.1002/trc2.12007

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