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Development of HPV(16,18,31,45) E5 and E7 peptides-based vaccines predicted by immunoinformatics tools

OBJECTIVES: Viral oncoproteins are ideal targets in therapeutic vaccines for functional inhibition of human papillomaviruses (HPVs). Herein, we designed the peptide constructs derived from E5 and E7 oncoproteins of high-risk HPV types 16, 18, 31 and 45 using the bioinformatics tools and investigated...

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Detalles Bibliográficos
Autores principales: Namvar, Ali, Panahi, Heidar Ali, Agi, Elnaz, Bolhassani, Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087594/
https://www.ncbi.nlm.nih.gov/pubmed/31915962
http://dx.doi.org/10.1007/s10529-020-02792-6