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Development of HPV(16,18,31,45) E5 and E7 peptides-based vaccines predicted by immunoinformatics tools
OBJECTIVES: Viral oncoproteins are ideal targets in therapeutic vaccines for functional inhibition of human papillomaviruses (HPVs). Herein, we designed the peptide constructs derived from E5 and E7 oncoproteins of high-risk HPV types 16, 18, 31 and 45 using the bioinformatics tools and investigated...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087594/ https://www.ncbi.nlm.nih.gov/pubmed/31915962 http://dx.doi.org/10.1007/s10529-020-02792-6 |