Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus

Animals were immunized with transmissible gastroenteritis virus conjugated with gold nanoparticles. The resultant antibodies had a higher titer than antibodies produced in response to native virus. Immunization with the antigen-colloidal gold complex led to a significant increase of the peritoneal m...

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Detalles Bibliográficos
Autores principales: Staroverov, S. A., Vidyasheva, I. V., Gabalov, K. P., Vasilenko, O. A., Laskavyi, V. N., Dykman, L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087599/
https://www.ncbi.nlm.nih.gov/pubmed/22448360
http://dx.doi.org/10.1007/s10517-011-1350-8
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author Staroverov, S. A.
Vidyasheva, I. V.
Gabalov, K. P.
Vasilenko, O. A.
Laskavyi, V. N.
Dykman, L. A.
author_facet Staroverov, S. A.
Vidyasheva, I. V.
Gabalov, K. P.
Vasilenko, O. A.
Laskavyi, V. N.
Dykman, L. A.
author_sort Staroverov, S. A.
collection PubMed
description Animals were immunized with transmissible gastroenteritis virus conjugated with gold nanoparticles. The resultant antibodies had a higher titer than antibodies produced in response to native virus. Immunization with the antigen-colloidal gold complex led to a significant increase of the peritoneal macrophages respiratory activity and of plasma IFN-γ level in immunized animals.
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spelling pubmed-70875992020-03-23 Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus Staroverov, S. A. Vidyasheva, I. V. Gabalov, K. P. Vasilenko, O. A. Laskavyi, V. N. Dykman, L. A. Bull Exp Biol Med Article Animals were immunized with transmissible gastroenteritis virus conjugated with gold nanoparticles. The resultant antibodies had a higher titer than antibodies produced in response to native virus. Immunization with the antigen-colloidal gold complex led to a significant increase of the peritoneal macrophages respiratory activity and of plasma IFN-γ level in immunized animals. Springer US 2011-08-23 2011 /pmc/articles/PMC7087599/ /pubmed/22448360 http://dx.doi.org/10.1007/s10517-011-1350-8 Text en © Springer Science+Business Media, Inc. 2011 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Staroverov, S. A.
Vidyasheva, I. V.
Gabalov, K. P.
Vasilenko, O. A.
Laskavyi, V. N.
Dykman, L. A.
Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus
title Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus
title_full Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus
title_fullStr Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus
title_full_unstemmed Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus
title_short Immunostimulatory Effect of Gold Nanoparticles Conjugated with Transmissible Gastroenteritis Virus
title_sort immunostimulatory effect of gold nanoparticles conjugated with transmissible gastroenteritis virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087599/
https://www.ncbi.nlm.nih.gov/pubmed/22448360
http://dx.doi.org/10.1007/s10517-011-1350-8
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