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Selected TLR7/8 agonist and type I interferon (IFN-α) cooperatively redefine the microglia transcriptome

BACKGROUND: Microglia, the primary immune cells of the central nervous system, exerts multiple functions to mediate many neurological diseases. Upon any detection of invading pathogen products (e.g., TLR agonists) or host-released signaling factors (e.g., interferon/IFN), these cells undergo an acti...

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Detalles Bibliográficos
Autores principales:	Khatun, Mst Reshma, Arifuzzaman, Sarder
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087773/ https://www.ncbi.nlm.nih.gov/pubmed/31190206 http://dx.doi.org/10.1007/s10787-019-00610-8

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