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On the different sources of cooperativity in pH titrating sites of a membrane protein channel
ABSTRACT. Cooperative interactions play a central role in the regulation of protein functions. Here we show that in multi-site systems like ion channels the application of the Hill formalism could require a combination of different experiments, even involving site-directed mutagenesis, to identify t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087919/ https://www.ncbi.nlm.nih.gov/pubmed/26987733 http://dx.doi.org/10.1140/epje/i2016-16029-2 |