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Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat

The tent-making bat hepatitis B virus (TBHBV) is a hepadnavirus closely related to human hepatitis B virus. The ecology of TBHBV is unclear. We show that it is widespread and highly diversified in Peters’ tent-making bats (Uroderma bilobatum) within Panama, while local prevalence varied significantl...

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Autores principales: Hiller, Thomas, Rasche, Andrea, Brändel, Stefan Dominik, König, Alexander, Jeworowski, Lara, Teague O’Mara, M., Cottontail, Veronika, Page, Rachel A., Glebe, Dieter, Drexler, Jan Felix, Tschapka, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088011/
https://www.ncbi.nlm.nih.gov/pubmed/30564998
http://dx.doi.org/10.1007/s10393-018-1387-5
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author Hiller, Thomas
Rasche, Andrea
Brändel, Stefan Dominik
König, Alexander
Jeworowski, Lara
Teague O’Mara, M.
Cottontail, Veronika
Page, Rachel A.
Glebe, Dieter
Drexler, Jan Felix
Tschapka, Marco
author_facet Hiller, Thomas
Rasche, Andrea
Brändel, Stefan Dominik
König, Alexander
Jeworowski, Lara
Teague O’Mara, M.
Cottontail, Veronika
Page, Rachel A.
Glebe, Dieter
Drexler, Jan Felix
Tschapka, Marco
author_sort Hiller, Thomas
collection PubMed
description The tent-making bat hepatitis B virus (TBHBV) is a hepadnavirus closely related to human hepatitis B virus. The ecology of TBHBV is unclear. We show that it is widespread and highly diversified in Peters’ tent-making bats (Uroderma bilobatum) within Panama, while local prevalence varied significantly between sample sites, ranging from 0 to 14.3%. Females showed significantly higher prevalence than males, and pregnant females were more often acutely infected than non-reproductive ones. The distribution of TBHBV in bats was significantly affected by forest cover, with higher infection rates in areas with lower forest cover. Our data indicate that loss of natural habitat may lead to positive feedback on the biotic factors driving infection possibility. These results underline the necessity of multidisciplinary studies for a better understanding of mechanisms in pathogen–host relationships and for predictions in disease ecology. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10393-018-1387-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-70880112020-03-23 Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat Hiller, Thomas Rasche, Andrea Brändel, Stefan Dominik König, Alexander Jeworowski, Lara Teague O’Mara, M. Cottontail, Veronika Page, Rachel A. Glebe, Dieter Drexler, Jan Felix Tschapka, Marco Ecohealth Original Contribution The tent-making bat hepatitis B virus (TBHBV) is a hepadnavirus closely related to human hepatitis B virus. The ecology of TBHBV is unclear. We show that it is widespread and highly diversified in Peters’ tent-making bats (Uroderma bilobatum) within Panama, while local prevalence varied significantly between sample sites, ranging from 0 to 14.3%. Females showed significantly higher prevalence than males, and pregnant females were more often acutely infected than non-reproductive ones. The distribution of TBHBV in bats was significantly affected by forest cover, with higher infection rates in areas with lower forest cover. Our data indicate that loss of natural habitat may lead to positive feedback on the biotic factors driving infection possibility. These results underline the necessity of multidisciplinary studies for a better understanding of mechanisms in pathogen–host relationships and for predictions in disease ecology. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10393-018-1387-5) contains supplementary material, which is available to authorized users. Springer US 2018-12-18 2019 /pmc/articles/PMC7088011/ /pubmed/30564998 http://dx.doi.org/10.1007/s10393-018-1387-5 Text en © EcoHealth Alliance 2018 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Contribution
Hiller, Thomas
Rasche, Andrea
Brändel, Stefan Dominik
König, Alexander
Jeworowski, Lara
Teague O’Mara, M.
Cottontail, Veronika
Page, Rachel A.
Glebe, Dieter
Drexler, Jan Felix
Tschapka, Marco
Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat
title Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat
title_full Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat
title_fullStr Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat
title_full_unstemmed Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat
title_short Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat
title_sort host biology and anthropogenic factors affect hepadnavirus infection in a neotropical bat
topic Original Contribution
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088011/
https://www.ncbi.nlm.nih.gov/pubmed/30564998
http://dx.doi.org/10.1007/s10393-018-1387-5
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