Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis

In the cerebrospinal fluid IgG of five patients with lymphomeningoradiculitis (Bannwarth's syndrome) and radiculomyelitis studied by immunoblot technique an oligoclonal pattern was found. Most of these oligoclonal bands were specific for Borrelia burgdorferi. In patients suffering from chronic...

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Autores principales: Martin, R., Martens, U., Sticht-Groh, V., Dörries, R., Krüger, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1988
Materias:
Original Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088014/
https://www.ncbi.nlm.nih.gov/pubmed/3373242
http://dx.doi.org/10.1007/BF00314352
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author Martin, R.
Martens, U.
Sticht-Groh, V.
Dörries, R.
Krüger, H.
author_facet Martin, R.
Martens, U.
Sticht-Groh, V.
Dörries, R.
Krüger, H.
author_sort Martin, R.
collection PubMed
description In the cerebrospinal fluid IgG of five patients with lymphomeningoradiculitis (Bannwarth's syndrome) and radiculomyelitis studied by immunoblot technique an oligoclonal pattern was found. Most of these oligoclonal bands were specific for Borrelia burgdorferi. In patients suffering from chronic meningoradiculomyelitis, repeated CSF examination by this technique showed persistent secretion of identical IgG bands. Thus, the specific humoral immune response and the disease activity could be documented over the course of the disease.
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spelling pubmed-70880142020-03-23 Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis Martin, R. Martens, U. Sticht-Groh, V. Dörries, R. Krüger, H. J Neurol Original Investigations In the cerebrospinal fluid IgG of five patients with lymphomeningoradiculitis (Bannwarth's syndrome) and radiculomyelitis studied by immunoblot technique an oligoclonal pattern was found. Most of these oligoclonal bands were specific for Borrelia burgdorferi. In patients suffering from chronic meningoradiculomyelitis, repeated CSF examination by this technique showed persistent secretion of identical IgG bands. Thus, the specific humoral immune response and the disease activity could be documented over the course of the disease. Springer-Verlag 1988 /pmc/articles/PMC7088014/ /pubmed/3373242 http://dx.doi.org/10.1007/BF00314352 Text en © Springer-Verlag 1988 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Investigations
Martin, R.
Martens, U.
Sticht-Groh, V.
Dörries, R.
Krüger, H.
Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis
title Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis
title_full Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis
title_fullStr Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis
title_full_unstemmed Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis
title_short Persistent intrathecal secretion of oligoclonal, Borrelia burgdorferi-specific IgG in chronic meningoradiculomyelitis
title_sort persistent intrathecal secretion of oligoclonal, borrelia burgdorferi-specific igg in chronic meningoradiculomyelitis
topic Original Investigations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088014/
https://www.ncbi.nlm.nih.gov/pubmed/3373242
http://dx.doi.org/10.1007/BF00314352
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