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Targeting of proteins to the Golgi apparatus
The Golgi apparatus maintains a highly organized structure in spite of the intense membrane traffic which flows into and out of this organelle. Resident Golgi proteins must have localization signals to ensure that they are targeted to the correct Golgi compartment and not swept further along the sec...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kluwer Academic Publishers
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088089/ https://www.ncbi.nlm.nih.gov/pubmed/7696842 http://dx.doi.org/10.1007/BF00731273 |
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author | Gleeson, Paul A. Teasdale, Rohan D. Burke, Jo |
author_facet | Gleeson, Paul A. Teasdale, Rohan D. Burke, Jo |
author_sort | Gleeson, Paul A. |
collection | PubMed |
description | The Golgi apparatus maintains a highly organized structure in spite of the intense membrane traffic which flows into and out of this organelle. Resident Golgi proteins must have localization signals to ensure that they are targeted to the correct Golgi compartment and not swept further along the secretory pathway. There are a number of distinct groups of Golgi membrane proteins, including glycosyltransferases, recyclingtrans-Golgi network proteins, peripheral membrane proteins, receptors and viral glycoproteins. Recent studies indicate that there are a number of different Golgi localization signals and mechanisms for retaining proteins to the Golgi apparatus. This review focuses on the current knowledge in this field. |
format | Online Article Text |
id | pubmed-7088089 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1994 |
publisher | Kluwer Academic Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-70880892020-03-23 Targeting of proteins to the Golgi apparatus Gleeson, Paul A. Teasdale, Rohan D. Burke, Jo Glycoconj J Glycopinion Mini-Review The Golgi apparatus maintains a highly organized structure in spite of the intense membrane traffic which flows into and out of this organelle. Resident Golgi proteins must have localization signals to ensure that they are targeted to the correct Golgi compartment and not swept further along the secretory pathway. There are a number of distinct groups of Golgi membrane proteins, including glycosyltransferases, recyclingtrans-Golgi network proteins, peripheral membrane proteins, receptors and viral glycoproteins. Recent studies indicate that there are a number of different Golgi localization signals and mechanisms for retaining proteins to the Golgi apparatus. This review focuses on the current knowledge in this field. Kluwer Academic Publishers 1994 /pmc/articles/PMC7088089/ /pubmed/7696842 http://dx.doi.org/10.1007/BF00731273 Text en © Chapman & Hall 1994 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Glycopinion Mini-Review Gleeson, Paul A. Teasdale, Rohan D. Burke, Jo Targeting of proteins to the Golgi apparatus |
title | Targeting of proteins to the Golgi apparatus |
title_full | Targeting of proteins to the Golgi apparatus |
title_fullStr | Targeting of proteins to the Golgi apparatus |
title_full_unstemmed | Targeting of proteins to the Golgi apparatus |
title_short | Targeting of proteins to the Golgi apparatus |
title_sort | targeting of proteins to the golgi apparatus |
topic | Glycopinion Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088089/ https://www.ncbi.nlm.nih.gov/pubmed/7696842 http://dx.doi.org/10.1007/BF00731273 |
work_keys_str_mv | AT gleesonpaula targetingofproteinstothegolgiapparatus AT teasdalerohand targetingofproteinstothegolgiapparatus AT burkejo targetingofproteinstothegolgiapparatus |