Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds

This review discusses the biological activity and synthesis of 1,9-diazaspiro[5.5]undecanes, including those ring-fused with arenes and heteroarenes and/or containing a carbonyl group at position 2. These compounds could be used for the treatment of obesity, pain, as well as various immune system, c...

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Detalles Bibliográficos
Autores principales: Blanco-Ania, Daniel, Heus, Rik, Rutjes, Floris P. J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088121/
https://www.ncbi.nlm.nih.gov/pubmed/32214420
http://dx.doi.org/10.1007/s10593-017-2133-6
Descripción
Sumario:This review discusses the biological activity and synthesis of 1,9-diazaspiro[5.5]undecanes, including those ring-fused with arenes and heteroarenes and/or containing a carbonyl group at position 2. These compounds could be used for the treatment of obesity, pain, as well as various immune system, cell signaling, cardiovascular, and psychotic disorders.

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