Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds

This review discusses the biological activity and synthesis of 1,9-diazaspiro[5.5]undecanes, including those ring-fused with arenes and heteroarenes and/or containing a carbonyl group at position 2. These compounds could be used for the treatment of obesity, pain, as well as various immune system, c...

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Detalles Bibliográficos
Autores principales: Blanco-Ania, Daniel, Heus, Rik, Rutjes, Floris P. J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088121/
https://www.ncbi.nlm.nih.gov/pubmed/32214420
http://dx.doi.org/10.1007/s10593-017-2133-6
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author Blanco-Ania, Daniel
Heus, Rik
Rutjes, Floris P. J. T.
author_facet Blanco-Ania, Daniel
Heus, Rik
Rutjes, Floris P. J. T.
author_sort Blanco-Ania, Daniel
collection PubMed
description This review discusses the biological activity and synthesis of 1,9-diazaspiro[5.5]undecanes, including those ring-fused with arenes and heteroarenes and/or containing a carbonyl group at position 2. These compounds could be used for the treatment of obesity, pain, as well as various immune system, cell signaling, cardiovascular, and psychotic disorders.
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spelling pubmed-70881212020-03-23 Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds Blanco-Ania, Daniel Heus, Rik Rutjes, Floris P. J. T. Chem Heterocycl Compd (N Y) Review This review discusses the biological activity and synthesis of 1,9-diazaspiro[5.5]undecanes, including those ring-fused with arenes and heteroarenes and/or containing a carbonyl group at position 2. These compounds could be used for the treatment of obesity, pain, as well as various immune system, cell signaling, cardiovascular, and psychotic disorders. Springer US 2017-10-05 2017 /pmc/articles/PMC7088121/ /pubmed/32214420 http://dx.doi.org/10.1007/s10593-017-2133-6 Text en © Springer Science+Business Media, LLC 2017 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Blanco-Ania, Daniel
Heus, Rik
Rutjes, Floris P. J. T.
Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds
title Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds
title_full Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds
title_fullStr Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds
title_full_unstemmed Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds
title_short Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds
title_sort privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro[5.5]undecane-containing compounds
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088121/
https://www.ncbi.nlm.nih.gov/pubmed/32214420
http://dx.doi.org/10.1007/s10593-017-2133-6
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AT rutjesflorispjt privilegedheterocyclesbioactivityandsynthesisof19diazaspiro55undecanecontainingcompounds

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