siRNA silencing of angiotensin-converting enzyme 2 reduced severe acute respiratory syndrome-associated coronavirus replications in Vero E6 cells

The outbreak of severe acute respiratory syndrome (SARS) in 2002–2003 has had a significant impact worldwide. No effective prophylaxis or treatment for SARS is available up to now. Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for SARS-associated coronavirus (SARS-CoV). By expressi...

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Detalles Bibliográficos
Autores principales: Lu, C.-Y., Huang, H.-Y., Yang, T.-H., Chang, L.-Y., Lee, C.-Y., Huang, L.-M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088151/
https://www.ncbi.nlm.nih.gov/pubmed/18449585
http://dx.doi.org/10.1007/s10096-008-0495-5

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