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Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus

The recent emergence and re-emergence of alphaviruses, in particular the chikungunya virus (CHIKV), in numerous countries has invoked a worldwide threat to human health, while simultaneously generating an economic burden on affected countries. There are currently no vaccines or effective drugs avail...

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Detalles Bibliográficos
Autores principales: Nguyen, Phuong T. V., Yu, Haibo, Keller, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088235/
https://www.ncbi.nlm.nih.gov/pubmed/24756552
http://dx.doi.org/10.1007/s00894-014-2216-6