Cystatins in Health and Diseases

The Cystatins constitute a large group of evolutionary related proteins with diverse biological activities. They have been recently realized as instrumental in myriad of pathophysiological conditions. They have been implicated in various pathological conditions. The degree of malignancy of various t...

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Detalles Bibliográficos
Autores principales: Shah, Aaliya, Bano, Bilqees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088278/
https://www.ncbi.nlm.nih.gov/pubmed/32214926
http://dx.doi.org/10.1007/s10989-008-9160-1
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author Shah, Aaliya
Bano, Bilqees
author_facet Shah, Aaliya
Bano, Bilqees
author_sort Shah, Aaliya
collection PubMed
description The Cystatins constitute a large group of evolutionary related proteins with diverse biological activities. They have been recently realized as instrumental in myriad of pathophysiological conditions. They have been implicated in various pathological conditions. The degree of malignancy of various types of cancer cells has been found to be inversely associated with the expression of cystatins. Cystatins have been found to have various antimicrobial, antiviral and immunomodulatory properties. Keeping in view as their being prospective drug targets and anti-disease options this review explores the role of cytoplasmic and cell secreted cystatins in various human diseases.
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spelling pubmed-70882782020-03-23 Cystatins in Health and Diseases Shah, Aaliya Bano, Bilqees Int J Pept Res Ther Article The Cystatins constitute a large group of evolutionary related proteins with diverse biological activities. They have been recently realized as instrumental in myriad of pathophysiological conditions. They have been implicated in various pathological conditions. The degree of malignancy of various types of cancer cells has been found to be inversely associated with the expression of cystatins. Cystatins have been found to have various antimicrobial, antiviral and immunomodulatory properties. Keeping in view as their being prospective drug targets and anti-disease options this review explores the role of cytoplasmic and cell secreted cystatins in various human diseases. Springer Netherlands 2008-11-13 2009 /pmc/articles/PMC7088278/ /pubmed/32214926 http://dx.doi.org/10.1007/s10989-008-9160-1 Text en © Springer Science+Business Media, LLC 2008 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Shah, Aaliya
Bano, Bilqees
Cystatins in Health and Diseases
title Cystatins in Health and Diseases
title_full Cystatins in Health and Diseases
title_fullStr Cystatins in Health and Diseases
title_full_unstemmed Cystatins in Health and Diseases
title_short Cystatins in Health and Diseases
title_sort cystatins in health and diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088278/
https://www.ncbi.nlm.nih.gov/pubmed/32214926
http://dx.doi.org/10.1007/s10989-008-9160-1
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