Characterization of the biochemical properties and identification of amino acids forming the catalytic center of 3C-like proteinase of porcine reproductive and respiratory syndrome virus

The non-structural protein 4 (Nsp4) of porcine reproductive and respiratory syndrome virus (PRRSV) functions as a 3C-like proteinase (3CLpro) and plays a pivotal role in gene expression and replication. We have examined the biochemical properties of PRRSV 3CLpro and identified those amino acid resid...

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Detalles Bibliográficos
Autores principales: Xu, Ao-Tian, Zhou, Yan-Jun, Li, Guo-Xin, Yu, Hai, Yan, Li-Ping, Tong, Guang-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088359/
https://www.ncbi.nlm.nih.gov/pubmed/20865444
http://dx.doi.org/10.1007/s10529-010-0370-1

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