Scorpion Venom–Toxins that Aid in Drug Development: A Review

Scorpion venom components have multifaceted orientation against bacterial, viral, fungal infections and other neuronal disorders. They can modulate the ion channels (K(+), Na(+), Cl(−), Ca(2+)) of our body and this concept has been hypothesized in formulating pharmaceuticals. The triumphant achievem...

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Detalles Bibliográficos
Autores principales: Ghosh, Arijit, Roy, Rini, Nandi, Monoswini, Mukhopadhyay, Ashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088386/
https://www.ncbi.nlm.nih.gov/pubmed/32214927
http://dx.doi.org/10.1007/s10989-018-9721-x
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author Ghosh, Arijit
Roy, Rini
Nandi, Monoswini
Mukhopadhyay, Ashis
author_facet Ghosh, Arijit
Roy, Rini
Nandi, Monoswini
Mukhopadhyay, Ashis
author_sort Ghosh, Arijit
collection PubMed
description Scorpion venom components have multifaceted orientation against bacterial, viral, fungal infections and other neuronal disorders. They can modulate the ion channels (K(+), Na(+), Cl(−), Ca(2+)) of our body and this concept has been hypothesized in formulating pharmaceuticals. The triumphant achievement of these venom components as formulated anticancer agent in Phase I and Phase II clinical trials allure researchers to excavate beneficial venom components prohibiting DNA replication in malignant tumor cells. This review brings forth the achievements of Science and Technology in classifying the venom components as therapeutics and further application in drug product development.
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spelling pubmed-70883862020-03-23 Scorpion Venom–Toxins that Aid in Drug Development: A Review Ghosh, Arijit Roy, Rini Nandi, Monoswini Mukhopadhyay, Ashis Int J Pept Res Ther Article Scorpion venom components have multifaceted orientation against bacterial, viral, fungal infections and other neuronal disorders. They can modulate the ion channels (K(+), Na(+), Cl(−), Ca(2+)) of our body and this concept has been hypothesized in formulating pharmaceuticals. The triumphant achievement of these venom components as formulated anticancer agent in Phase I and Phase II clinical trials allure researchers to excavate beneficial venom components prohibiting DNA replication in malignant tumor cells. This review brings forth the achievements of Science and Technology in classifying the venom components as therapeutics and further application in drug product development. Springer Netherlands 2018-06-05 2019 /pmc/articles/PMC7088386/ /pubmed/32214927 http://dx.doi.org/10.1007/s10989-018-9721-x Text en © Springer Science+Business Media, LLC, part of Springer Nature 2018 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Ghosh, Arijit
Roy, Rini
Nandi, Monoswini
Mukhopadhyay, Ashis
Scorpion Venom–Toxins that Aid in Drug Development: A Review
title Scorpion Venom–Toxins that Aid in Drug Development: A Review
title_full Scorpion Venom–Toxins that Aid in Drug Development: A Review
title_fullStr Scorpion Venom–Toxins that Aid in Drug Development: A Review
title_full_unstemmed Scorpion Venom–Toxins that Aid in Drug Development: A Review
title_short Scorpion Venom–Toxins that Aid in Drug Development: A Review
title_sort scorpion venom–toxins that aid in drug development: a review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088386/
https://www.ncbi.nlm.nih.gov/pubmed/32214927
http://dx.doi.org/10.1007/s10989-018-9721-x
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AT mukhopadhyayashis scorpionvenomtoxinsthataidindrugdevelopmentareview

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