Cargando…

Apocynin protects endothelial cells from endoplasmic reticulum stress-induced apoptosis via IRE1α engagement

Endoplasmic reticulum (ER) stress-induced endothelial cell (EC) apoptosis has been implicated in a variety of human diseases. In addition to being regarded as an NADPH oxidase (NOX) inhibitor, apocynin (APO) exhibits an anti-apoptotic effect in various cells. The present study aimed to identify the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Jie, Zhang, Weijin, Liu, Xiaohui, Wu, Lili, He, Guangting, Li, Peixin, Guo, Xiaohua, Chen, Zhongqing, Huang, Qiaobing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088535/ https://www.ncbi.nlm.nih.gov/pubmed/29696609 http://dx.doi.org/10.1007/s11010-018-3362-4

Ejemplares similares

Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment
por: Banerjee, Aditi, et al.
Publicado: (2016)

IRE1α is an endogenous substrate of endoplasmic reticulum-associated degradation
por: Sun, Shengyi, et al.
Publicado: (2015)

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress
por: Grey, Michael J., et al.
Publicado: (2020)

IRES-Dependent Translational Control during Virus-Induced Endoplasmic Reticulum Stress and Apoptosis
por: Hanson, Paul J., et al.
Publicado: (2012)

Hyperoxia induces endoplasmic reticulum stress-associated apoptosis via the IRE1α pathway in rats with bronchopulmonary dysplasia
por: Tong, Xin, et al.
Publicado: (2021)

Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
por: Liu, Xiaohui, et al.
Publicado: (2022)

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
por: Le Thomas, Adrien, et al.
Publicado: (2021)

IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases
por: Junjappa, Raghu Patil, et al.
Publicado: (2018)

Sirt1 Inhibits Oxidative Stress in Vascular Endothelial Cells
por: Zhang, Weijin, et al.
Publicado: (2017)

Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
por: Sundaram, Arunkumar, et al.
Publicado: (2018)

Melatonin promotes sirtuin 1 expression and inhibits IRE1α–XBP1S–CHOP to reduce endoplasmic reticulum stress–mediated apoptosis in chondrocytes
por: Qin, Kunpeng, et al.
Publicado: (2022)

IRE1α siRNA relieves endoplasmic reticulum stress-induced apoptosis and alleviates diabetic peripheral neuropathy in vivo and in vitro
por: Yao, Weijie, et al.
Publicado: (2018)

CaMKII orchestrates endoplasmic reticulum stress and apoptosis in doxorubicin‐induced cardiotoxicity by regulating the IRE1α/XBP1s pathway
por: Kong, Lingheng, et al.
Publicado: (2022)

A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress
por: Li, Xia, et al.
Publicado: (2020)

Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction
por: Zhang, Weijin, et al.
Publicado: (2017)

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability
por: Liu, Jiang, et al.
Publicado: (2017)

Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells
por: Márquez, Saioa, et al.
Publicado: (2017)

Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation
por: Riaz, Thoufiqul Alam, et al.
Publicado: (2020)

Induction of the Endoplasmic-Reticulum-Stress Response: MicroRNA-34a Targeting of the IRE1α-Branch
por: Krammes, Lena, et al.
Publicado: (2020)

IRE1α and IGF signaling predict resistance to an endoplasmic reticulum stress-inducing drug in glioblastoma cells
por: Rodvold, Jeffrey J., et al.
Publicado: (2020)

Melatonin Improves Endoplasmic Reticulum Stress-Mediated IRE1α Pathway in Zücker Diabetic Fatty Rat
por: Aouichat, Samira, et al.
Publicado: (2021)

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity
por: Rubio, Claudia, et al.
Publicado: (2011)

Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress
por: Zhou, Zhixin, et al.
Publicado: (2022)

Quercetin Affects Hsp70/IRE1α Mediated Protection from Death Induced by Endoplasmic Reticulum Stress
por: Storniolo, Antonello, et al.
Publicado: (2015)

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway
por: Namba, Takushi, et al.
Publicado: (2015)

Activation of the endoplasmic reticulum stress sensor IRE1α by the vaccine adjuvant AS03 contributes to its immunostimulatory properties
por: Givord, Charlotte, et al.
Publicado: (2018)

Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers
por: Belyy, Vladislav, et al.
Publicado: (2022)

The endoplasmic reticulum stress sensor IRE1α modulates macrophage metabolic function during Brucella abortus infection
por: Guimarães, Erika S., et al.
Publicado: (2023)

Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling
por: Cohen, Nir, et al.
Publicado: (2017)

The natural product salicin alleviates osteoarthritis progression by binding to IRE1α and inhibiting endoplasmic reticulum stress through the IRE1α-IκBα-p65 signaling pathway
por: Zhu, Zhenglin, et al.
Publicado: (2022)

Endoplasmic reticulum stress and apoptosis
por: Faitova, Jitka, et al.
Publicado: (2006)

α-synuclein induces apoptosis of astrocytes by causing dysfunction of the endoplasmic reticulum-Golgi compartment
por: Liu, Mei, et al.
Publicado: (2018)

RNAi Screen of Endoplasmic Reticulum–Associated Host Factors Reveals a Role for IRE1α in Supporting Brucella Replication
por: Qin, Qing-Ming, et al.
Publicado: (2008)

Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response
por: Luo, Ruixi, et al.
Publicado: (2023)

Improvement of Pharmacokinetics Behavior of Apocynin by Nitrone Derivatization: Comparative Pharmacokinetics of Nitrone-Apocynin and its Parent Apocynin in Rats
por: Wang, Kaiyu, et al.
Publicado: (2013)

A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1
por: Kimata, Yukio, et al.
Publicado: (2004)

Transdifferentiation mediated tumor suppression by the endoplasmic reticulum stress sensor IRE-1 in C. elegans
por: Levi-Ferber, Mor, et al.
Publicado: (2015)

Probing natural variation of IRE1 expression and endoplasmic reticulum stress responses in Arabidopsis accessions
por: Afrin, Taiaba, et al.
Publicado: (2020)

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK and IRE1α-mediated unfolded protein response
por: Jwa, Miri, et al.
Publicado: (2012)

Endoplasmic reticulum stress enhances fibrosis through IRE1α‐mediated degradation of miR‐150 and XBP‐1 splicing
por: Heindryckx, Femke, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_422k7mkle4k19lnf4unqnsav8i