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Hepatitis C virus NS4A inhibits cap-dependent and the viral IRES-mediated translation through interacting with eukaryotic elongation factor 1A

The genomic RNA of hepatitis C virus (HCV) encodes the viral polyprotein precursor that undergoes proteolytic cleavage into structural and nonstructural proteins by cellular and the viral NS3 and NS2-3 proteases. Nonstructural protein 4A (NS4A) is a cofactor of the NS3 serine protease and has been d...

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Detalles Bibliográficos
Autores principales:	Kou, Yi-Hen, Chou, Shang-Min, Wang, Yi-Ming, Chang, Ya-Tzu, Huang, Shao-Yong, Jung, Mei-Ying, Huang, Yu-Hsu, Chen, Mei-Ru, Chang, Ming-Fu, Chang, Shin C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Kluwer Academic Publishers 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088589/ https://www.ncbi.nlm.nih.gov/pubmed/16927014 http://dx.doi.org/10.1007/s11373-006-9104-8

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