Cargando…

Drosophila melanogaster as a model for studying the function of animal viral proteins

Studies in which Drosophila melanogaster individuals carrying transgenes of animal viruses were used to analyze the action of animal viral proteins on the cell are reviewed. The data presented suggest that host specificity of viruses is determined by their proteins responsible for the penetration of...

Descripción completa

Detalles Bibliográficos
Autores principales: Omel’yanchuk, L. V., Yudina, O. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP MAIK Nauka/Interperiodica 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088594/
https://www.ncbi.nlm.nih.gov/pubmed/32214757
http://dx.doi.org/10.1134/S1022795411040090
_version_ 1783509569175027712
author Omel’yanchuk, L. V.
Yudina, O. S.
author_facet Omel’yanchuk, L. V.
Yudina, O. S.
author_sort Omel’yanchuk, L. V.
collection PubMed
description Studies in which Drosophila melanogaster individuals carrying transgenes of animal viruses were used to analyze the action of animal viral proteins on the cell are reviewed. The data presented suggest that host specificity of viruses is determined by their proteins responsible for the penetration of the virus into the cell, while viral proteins responsible for interactions with the host cell are much less host-specific. Due to this, the model of Drosophila with its developed system of searching for genetic interactions can be used to find intracellular targets for the action of viral proteins of the second group.
format Online
Article
Text
id pubmed-7088594
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher SP MAIK Nauka/Interperiodica
record_format MEDLINE/PubMed
spelling pubmed-70885942020-03-23 Drosophila melanogaster as a model for studying the function of animal viral proteins Omel’yanchuk, L. V. Yudina, O. S. Russ J Genet Reviews and Theoretical Articles Studies in which Drosophila melanogaster individuals carrying transgenes of animal viruses were used to analyze the action of animal viral proteins on the cell are reviewed. The data presented suggest that host specificity of viruses is determined by their proteins responsible for the penetration of the virus into the cell, while viral proteins responsible for interactions with the host cell are much less host-specific. Due to this, the model of Drosophila with its developed system of searching for genetic interactions can be used to find intracellular targets for the action of viral proteins of the second group. SP MAIK Nauka/Interperiodica 2011-07-16 2011 /pmc/articles/PMC7088594/ /pubmed/32214757 http://dx.doi.org/10.1134/S1022795411040090 Text en © Pleiades Publishing, Ltd. 2011 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Reviews and Theoretical Articles
Omel’yanchuk, L. V.
Yudina, O. S.
Drosophila melanogaster as a model for studying the function of animal viral proteins
title Drosophila melanogaster as a model for studying the function of animal viral proteins
title_full Drosophila melanogaster as a model for studying the function of animal viral proteins
title_fullStr Drosophila melanogaster as a model for studying the function of animal viral proteins
title_full_unstemmed Drosophila melanogaster as a model for studying the function of animal viral proteins
title_short Drosophila melanogaster as a model for studying the function of animal viral proteins
title_sort drosophila melanogaster as a model for studying the function of animal viral proteins
topic Reviews and Theoretical Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088594/
https://www.ncbi.nlm.nih.gov/pubmed/32214757
http://dx.doi.org/10.1134/S1022795411040090
work_keys_str_mv AT omelyanchuklv drosophilamelanogasterasamodelforstudyingthefunctionofanimalviralproteins
AT yudinaos drosophilamelanogasterasamodelforstudyingthefunctionofanimalviralproteins