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Drosophila melanogaster as a model for studying the function of animal viral proteins
Studies in which Drosophila melanogaster individuals carrying transgenes of animal viruses were used to analyze the action of animal viral proteins on the cell are reviewed. The data presented suggest that host specificity of viruses is determined by their proteins responsible for the penetration of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP MAIK Nauka/Interperiodica
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088594/ https://www.ncbi.nlm.nih.gov/pubmed/32214757 http://dx.doi.org/10.1134/S1022795411040090 |
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author | Omel’yanchuk, L. V. Yudina, O. S. |
author_facet | Omel’yanchuk, L. V. Yudina, O. S. |
author_sort | Omel’yanchuk, L. V. |
collection | PubMed |
description | Studies in which Drosophila melanogaster individuals carrying transgenes of animal viruses were used to analyze the action of animal viral proteins on the cell are reviewed. The data presented suggest that host specificity of viruses is determined by their proteins responsible for the penetration of the virus into the cell, while viral proteins responsible for interactions with the host cell are much less host-specific. Due to this, the model of Drosophila with its developed system of searching for genetic interactions can be used to find intracellular targets for the action of viral proteins of the second group. |
format | Online Article Text |
id | pubmed-7088594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | SP MAIK Nauka/Interperiodica |
record_format | MEDLINE/PubMed |
spelling | pubmed-70885942020-03-23 Drosophila melanogaster as a model for studying the function of animal viral proteins Omel’yanchuk, L. V. Yudina, O. S. Russ J Genet Reviews and Theoretical Articles Studies in which Drosophila melanogaster individuals carrying transgenes of animal viruses were used to analyze the action of animal viral proteins on the cell are reviewed. The data presented suggest that host specificity of viruses is determined by their proteins responsible for the penetration of the virus into the cell, while viral proteins responsible for interactions with the host cell are much less host-specific. Due to this, the model of Drosophila with its developed system of searching for genetic interactions can be used to find intracellular targets for the action of viral proteins of the second group. SP MAIK Nauka/Interperiodica 2011-07-16 2011 /pmc/articles/PMC7088594/ /pubmed/32214757 http://dx.doi.org/10.1134/S1022795411040090 Text en © Pleiades Publishing, Ltd. 2011 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Reviews and Theoretical Articles Omel’yanchuk, L. V. Yudina, O. S. Drosophila melanogaster as a model for studying the function of animal viral proteins |
title | Drosophila melanogaster as a model for studying the function of animal viral proteins |
title_full | Drosophila melanogaster as a model for studying the function of animal viral proteins |
title_fullStr | Drosophila melanogaster as a model for studying the function of animal viral proteins |
title_full_unstemmed | Drosophila melanogaster as a model for studying the function of animal viral proteins |
title_short | Drosophila melanogaster as a model for studying the function of animal viral proteins |
title_sort | drosophila melanogaster as a model for studying the function of animal viral proteins |
topic | Reviews and Theoretical Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088594/ https://www.ncbi.nlm.nih.gov/pubmed/32214757 http://dx.doi.org/10.1134/S1022795411040090 |
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