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An efficient three-component, one-pot synthesis of 2-alkylthio-4-amino-5-cyano-6-aryl(alkyl)pyrimidines in water

A convenient and practical method for the synthesis of 2-alkylthio-4-amino-5-cyano-6-aryl(alkyl)pyrimidines has been developed via a three-component, one-pot reaction from aldehydes, malononitrile and S-alkylisothiouronium salts in water at room temperature. A series of polysubstituted pyrimidines w...

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Detalles Bibliográficos
Autores principales:	Li, Qiao-Yan, Ge, Ze-Mei, Cheng, Tie-Ming, Li, Run-Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2012
Materias:	Full-Length Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088670/ https://www.ncbi.nlm.nih.gov/pubmed/22740103 http://dx.doi.org/10.1007/s11030-012-9376-z

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