Detection of bat hepatitis E virus RNA in microbats in Japan

Several recent studies have reported that various bat species harbor bat hepatitis E viruses (BatHEV) belonging to the family Hepeviridae, which also contains human hepatitis E virus (HEV). The distribution and ecology of BatHEV are not well known. Here, we collected and screened 81 bat fecal sample...

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Autores principales: Kobayashi, Tomoya, Murakami, Shin, Yamamoto, Terumasa, Mineshita, Ko, Sakuyama, Muneki, Sasaki, Reiko, Maeda, Ken, Horimoto, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088820/
https://www.ncbi.nlm.nih.gov/pubmed/29845506
http://dx.doi.org/10.1007/s11262-018-1577-9
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author Kobayashi, Tomoya
Murakami, Shin
Yamamoto, Terumasa
Mineshita, Ko
Sakuyama, Muneki
Sasaki, Reiko
Maeda, Ken
Horimoto, Taisuke
author_facet Kobayashi, Tomoya
Murakami, Shin
Yamamoto, Terumasa
Mineshita, Ko
Sakuyama, Muneki
Sasaki, Reiko
Maeda, Ken
Horimoto, Taisuke
author_sort Kobayashi, Tomoya
collection PubMed
description Several recent studies have reported that various bat species harbor bat hepatitis E viruses (BatHEV) belonging to the family Hepeviridae, which also contains human hepatitis E virus (HEV). The distribution and ecology of BatHEV are not well known. Here, we collected and screened 81 bat fecal samples from nine bat species in Japan to detect BatHEV RNA by RT-PCR using HEV-specific primers, and detected three positive samples. Sequence and phylogenetic analyses indicated that these three viruses were BatHEVs belonging to genus Orthohepevirus D like other BatHEV strains reported earlier in various countries. These data support the first detection of BatHEVs in Japanese microbats, indicating their wide geographical distribution among multiple bat species.
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spelling pubmed-70888202020-03-23 Detection of bat hepatitis E virus RNA in microbats in Japan Kobayashi, Tomoya Murakami, Shin Yamamoto, Terumasa Mineshita, Ko Sakuyama, Muneki Sasaki, Reiko Maeda, Ken Horimoto, Taisuke Virus Genes Article Several recent studies have reported that various bat species harbor bat hepatitis E viruses (BatHEV) belonging to the family Hepeviridae, which also contains human hepatitis E virus (HEV). The distribution and ecology of BatHEV are not well known. Here, we collected and screened 81 bat fecal samples from nine bat species in Japan to detect BatHEV RNA by RT-PCR using HEV-specific primers, and detected three positive samples. Sequence and phylogenetic analyses indicated that these three viruses were BatHEVs belonging to genus Orthohepevirus D like other BatHEV strains reported earlier in various countries. These data support the first detection of BatHEVs in Japanese microbats, indicating their wide geographical distribution among multiple bat species. Springer US 2018-05-29 2018 /pmc/articles/PMC7088820/ /pubmed/29845506 http://dx.doi.org/10.1007/s11262-018-1577-9 Text en © Springer Science+Business Media, LLC, part of Springer Nature 2018 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Kobayashi, Tomoya
Murakami, Shin
Yamamoto, Terumasa
Mineshita, Ko
Sakuyama, Muneki
Sasaki, Reiko
Maeda, Ken
Horimoto, Taisuke
Detection of bat hepatitis E virus RNA in microbats in Japan
title Detection of bat hepatitis E virus RNA in microbats in Japan
title_full Detection of bat hepatitis E virus RNA in microbats in Japan
title_fullStr Detection of bat hepatitis E virus RNA in microbats in Japan
title_full_unstemmed Detection of bat hepatitis E virus RNA in microbats in Japan
title_short Detection of bat hepatitis E virus RNA in microbats in Japan
title_sort detection of bat hepatitis e virus rna in microbats in japan
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088820/
https://www.ncbi.nlm.nih.gov/pubmed/29845506
http://dx.doi.org/10.1007/s11262-018-1577-9
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