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Olfaction and anosmia in rhinosinusitis

Olfactory disorders can cause serious consequences from the inability to detect many olfactory warning signals (eg, smoke, spoiled food, and gas leaks) and can significantly impact nutritional status, eating satisfaction, and many other issues related to quality of life. More than 200,000 people a y...

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Detalles Bibliográficos
Autor principal: Dalton, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Medicine Group 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088987/
https://www.ncbi.nlm.nih.gov/pubmed/15056406
http://dx.doi.org/10.1007/s11882-004-0031-3
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author Dalton, Pamela
author_facet Dalton, Pamela
author_sort Dalton, Pamela
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description Olfactory disorders can cause serious consequences from the inability to detect many olfactory warning signals (eg, smoke, spoiled food, and gas leaks) and can significantly impact nutritional status, eating satisfaction, and many other issues related to quality of life. More than 200,000 people a year seek treatment for impaired olfactory ability, and available evidence suggests this figure is a significant underestimate of those affected. Rhinitis and rhinosinusitis are the primary etiologies for olfactory loss or distortion among patients presenting to chemosensory clinics, and they are among the most common chronic medical conditions in the United States, affecting an estimated 33 million people. Both allergic and nonallergic rhinitis/rhinosinusitis can result in diminished, distorted, or absent olfactory ability. Current therapies are only partially or transiently effective in reversing olfactory loss. The underlying mechanisms by which rhinitis/rhinosinusitis impact olfactory ability are likely to be multifactorial and might include altered air flow and odor deposition, changes in mucus composition, and effects of inflammatory mediators on receptor cell differentiation, maturation, or function.
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spelling pubmed-70889872020-03-23 Olfaction and anosmia in rhinosinusitis Dalton, Pamela Curr Allergy Asthma Rep Article Olfactory disorders can cause serious consequences from the inability to detect many olfactory warning signals (eg, smoke, spoiled food, and gas leaks) and can significantly impact nutritional status, eating satisfaction, and many other issues related to quality of life. More than 200,000 people a year seek treatment for impaired olfactory ability, and available evidence suggests this figure is a significant underestimate of those affected. Rhinitis and rhinosinusitis are the primary etiologies for olfactory loss or distortion among patients presenting to chemosensory clinics, and they are among the most common chronic medical conditions in the United States, affecting an estimated 33 million people. Both allergic and nonallergic rhinitis/rhinosinusitis can result in diminished, distorted, or absent olfactory ability. Current therapies are only partially or transiently effective in reversing olfactory loss. The underlying mechanisms by which rhinitis/rhinosinusitis impact olfactory ability are likely to be multifactorial and might include altered air flow and odor deposition, changes in mucus composition, and effects of inflammatory mediators on receptor cell differentiation, maturation, or function. Current Medicine Group 2004 /pmc/articles/PMC7088987/ /pubmed/15056406 http://dx.doi.org/10.1007/s11882-004-0031-3 Text en © Current Science Inc 2004 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Dalton, Pamela
Olfaction and anosmia in rhinosinusitis
title Olfaction and anosmia in rhinosinusitis
title_full Olfaction and anosmia in rhinosinusitis
title_fullStr Olfaction and anosmia in rhinosinusitis
title_full_unstemmed Olfaction and anosmia in rhinosinusitis
title_short Olfaction and anosmia in rhinosinusitis
title_sort olfaction and anosmia in rhinosinusitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088987/
https://www.ncbi.nlm.nih.gov/pubmed/15056406
http://dx.doi.org/10.1007/s11882-004-0031-3
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