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Genomic characterization of a proventriculitis-associated infectious bronchitis coronavirus

Transmissible proventriculitis associated with infectious bronchitis virus (IBV) was at first seen in eastern China in mid-1995, and is now endemic in China. Herein, the complete genome sequence of a proventiculitis-associated infectious bronchitis coronavirus (ZJ971) was sequenced and analyzed. Com...

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Detalles Bibliográficos
Autores principales: Xiao, Chao-ting, Liu, Ran, Song, Zhu-yuan, Liao, Min, Zhou, Ji-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089038/
https://www.ncbi.nlm.nih.gov/pubmed/20195741
http://dx.doi.org/10.1007/s11262-010-0461-z
Descripción
Sumario:Transmissible proventriculitis associated with infectious bronchitis virus (IBV) was at first seen in eastern China in mid-1995, and is now endemic in China. Herein, the complete genome sequence of a proventiculitis-associated infectious bronchitis coronavirus (ZJ971) was sequenced and analyzed. Compared with the genome of the vaccine strain H120, ZJ971 had 54 nucleotide substitutions and a deletion in the 3′-UTR. The substitutions were in the regions of nsp2–nsp5, nsp7, nsp12, nsp13, nsp15, S and N genes, and the untranslating region. The results indicated that ZJ971 could be a variant of IBV strain H120.