Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections

Phenomenon of RNA-induced gene silencing is a highly conservative mechanism among eukaryotic organisms. Several classes of small RNAs (siRNAs and miRNAs) 21–25 nt in length, which play a significant role in the processes of development of an organism, occurred important components of antiviral defen...

Descripción completa

Detalles Bibliográficos
Autores principales: Krulko, I., Ustyanenko, D., Polischuk, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Allerton Press, Inc. 2009
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089099/
https://www.ncbi.nlm.nih.gov/pubmed/32214541
http://dx.doi.org/10.3103/S0095452709010113
_version_ 1783509661498998784
author Krulko, I.
Ustyanenko, D.
Polischuk, V.
author_facet Krulko, I.
Ustyanenko, D.
Polischuk, V.
author_sort Krulko, I.
collection PubMed
description Phenomenon of RNA-induced gene silencing is a highly conservative mechanism among eukaryotic organisms. Several classes of small RNAs (siRNAs and miRNAs) 21–25 nt in length, which play a significant role in the processes of development of an organism, occurred important components of antiviral defence in animals and plants. This review shortly describes the main stages of gene silencing mechanism, features of antiviral RNA silencing in plants, invertebrates, mammals, ways of suppression of RNA-interference by viruses, as well as possible approaches of utilization of abovementioned phenomenon for struggling against viral infections.
format Online
Article
Text
id pubmed-7089099
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Allerton Press, Inc.
record_format MEDLINE/PubMed
spelling pubmed-70890992020-03-23 Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections Krulko, I. Ustyanenko, D. Polischuk, V. Cytol. Genet Review Articles Phenomenon of RNA-induced gene silencing is a highly conservative mechanism among eukaryotic organisms. Several classes of small RNAs (siRNAs and miRNAs) 21–25 nt in length, which play a significant role in the processes of development of an organism, occurred important components of antiviral defence in animals and plants. This review shortly describes the main stages of gene silencing mechanism, features of antiviral RNA silencing in plants, invertebrates, mammals, ways of suppression of RNA-interference by viruses, as well as possible approaches of utilization of abovementioned phenomenon for struggling against viral infections. Allerton Press, Inc. 2009-02-22 2009 /pmc/articles/PMC7089099/ /pubmed/32214541 http://dx.doi.org/10.3103/S0095452709010113 Text en © Allerton Press, Inc. 2009 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Articles
Krulko, I.
Ustyanenko, D.
Polischuk, V.
Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections
title Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections
title_full Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections
title_fullStr Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections
title_full_unstemmed Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections
title_short Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections
title_sort role of sirnas and mirnas in the processes of rna-mediated gene silencing during viral infections
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089099/
https://www.ncbi.nlm.nih.gov/pubmed/32214541
http://dx.doi.org/10.3103/S0095452709010113
work_keys_str_mv AT krulkoi roleofsirnasandmirnasintheprocessesofrnamediatedgenesilencingduringviralinfections
AT ustyanenkod roleofsirnasandmirnasintheprocessesofrnamediatedgenesilencingduringviralinfections
AT polischukv roleofsirnasandmirnasintheprocessesofrnamediatedgenesilencingduringviralinfections

Ejemplares similares