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Thoughts on the pathophysiology of nonallergic rhinitis
Nonallergic noninfectious rhinitis is a diagnosis by exclusion, meaning that a number of poorly defined nasal conditions that have in common allergy and infection as a cause of the rhinitis have been excluded. The etiology of some subgroups of nonallergic noninfectious rhinitis, like nonallergic rhi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Current Medicine Group
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089100/ https://www.ncbi.nlm.nih.gov/pubmed/11918861 http://dx.doi.org/10.1007/s11882-002-0020-3 |
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author | Fokkens, Wytske J. |
author_facet | Fokkens, Wytske J. |
author_sort | Fokkens, Wytske J. |
collection | PubMed |
description | Nonallergic noninfectious rhinitis is a diagnosis by exclusion, meaning that a number of poorly defined nasal conditions that have in common allergy and infection as a cause of the rhinitis have been excluded. The etiology of some subgroups of nonallergic noninfectious rhinitis, like nonallergic rhinitis with eosinophilia (NARES) and drug-induced rhinitis, are quite well defined, but in the majority of the patients, the etiology and pathophysiology are unknown. These patients are classified as idiopathic rhinitis patients. A careful determination of the intensity of the symptoms combined with modern diagnostic tools enables us to discriminate idiopathic rhinitis patients from normal controls. This review discusses the possible pathophysicologic mechanisms of nonallergic noninfectious rhinitis, with emphasis on idiopathic rhinitis. |
format | Online Article Text |
id | pubmed-7089100 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | Current Medicine Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-70891002020-03-23 Thoughts on the pathophysiology of nonallergic rhinitis Fokkens, Wytske J. Curr Allergy Asthma Rep Article Nonallergic noninfectious rhinitis is a diagnosis by exclusion, meaning that a number of poorly defined nasal conditions that have in common allergy and infection as a cause of the rhinitis have been excluded. The etiology of some subgroups of nonallergic noninfectious rhinitis, like nonallergic rhinitis with eosinophilia (NARES) and drug-induced rhinitis, are quite well defined, but in the majority of the patients, the etiology and pathophysiology are unknown. These patients are classified as idiopathic rhinitis patients. A careful determination of the intensity of the symptoms combined with modern diagnostic tools enables us to discriminate idiopathic rhinitis patients from normal controls. This review discusses the possible pathophysicologic mechanisms of nonallergic noninfectious rhinitis, with emphasis on idiopathic rhinitis. Current Medicine Group 2002 /pmc/articles/PMC7089100/ /pubmed/11918861 http://dx.doi.org/10.1007/s11882-002-0020-3 Text en © Current Science Inc 2002 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Fokkens, Wytske J. Thoughts on the pathophysiology of nonallergic rhinitis |
title | Thoughts on the pathophysiology of nonallergic rhinitis |
title_full | Thoughts on the pathophysiology of nonallergic rhinitis |
title_fullStr | Thoughts on the pathophysiology of nonallergic rhinitis |
title_full_unstemmed | Thoughts on the pathophysiology of nonallergic rhinitis |
title_short | Thoughts on the pathophysiology of nonallergic rhinitis |
title_sort | thoughts on the pathophysiology of nonallergic rhinitis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089100/ https://www.ncbi.nlm.nih.gov/pubmed/11918861 http://dx.doi.org/10.1007/s11882-002-0020-3 |
work_keys_str_mv | AT fokkenswytskej thoughtsonthepathophysiologyofnonallergicrhinitis |