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Thoughts on the pathophysiology of nonallergic rhinitis

Nonallergic noninfectious rhinitis is a diagnosis by exclusion, meaning that a number of poorly defined nasal conditions that have in common allergy and infection as a cause of the rhinitis have been excluded. The etiology of some subgroups of nonallergic noninfectious rhinitis, like nonallergic rhi...

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Autor principal: Fokkens, Wytske J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Medicine Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089100/
https://www.ncbi.nlm.nih.gov/pubmed/11918861
http://dx.doi.org/10.1007/s11882-002-0020-3
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author Fokkens, Wytske J.
author_facet Fokkens, Wytske J.
author_sort Fokkens, Wytske J.
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description Nonallergic noninfectious rhinitis is a diagnosis by exclusion, meaning that a number of poorly defined nasal conditions that have in common allergy and infection as a cause of the rhinitis have been excluded. The etiology of some subgroups of nonallergic noninfectious rhinitis, like nonallergic rhinitis with eosinophilia (NARES) and drug-induced rhinitis, are quite well defined, but in the majority of the patients, the etiology and pathophysiology are unknown. These patients are classified as idiopathic rhinitis patients. A careful determination of the intensity of the symptoms combined with modern diagnostic tools enables us to discriminate idiopathic rhinitis patients from normal controls. This review discusses the possible pathophysicologic mechanisms of nonallergic noninfectious rhinitis, with emphasis on idiopathic rhinitis.
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spelling pubmed-70891002020-03-23 Thoughts on the pathophysiology of nonallergic rhinitis Fokkens, Wytske J. Curr Allergy Asthma Rep Article Nonallergic noninfectious rhinitis is a diagnosis by exclusion, meaning that a number of poorly defined nasal conditions that have in common allergy and infection as a cause of the rhinitis have been excluded. The etiology of some subgroups of nonallergic noninfectious rhinitis, like nonallergic rhinitis with eosinophilia (NARES) and drug-induced rhinitis, are quite well defined, but in the majority of the patients, the etiology and pathophysiology are unknown. These patients are classified as idiopathic rhinitis patients. A careful determination of the intensity of the symptoms combined with modern diagnostic tools enables us to discriminate idiopathic rhinitis patients from normal controls. This review discusses the possible pathophysicologic mechanisms of nonallergic noninfectious rhinitis, with emphasis on idiopathic rhinitis. Current Medicine Group 2002 /pmc/articles/PMC7089100/ /pubmed/11918861 http://dx.doi.org/10.1007/s11882-002-0020-3 Text en © Current Science Inc 2002 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Fokkens, Wytske J.
Thoughts on the pathophysiology of nonallergic rhinitis
title Thoughts on the pathophysiology of nonallergic rhinitis
title_full Thoughts on the pathophysiology of nonallergic rhinitis
title_fullStr Thoughts on the pathophysiology of nonallergic rhinitis
title_full_unstemmed Thoughts on the pathophysiology of nonallergic rhinitis
title_short Thoughts on the pathophysiology of nonallergic rhinitis
title_sort thoughts on the pathophysiology of nonallergic rhinitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089100/
https://www.ncbi.nlm.nih.gov/pubmed/11918861
http://dx.doi.org/10.1007/s11882-002-0020-3
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