Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide

Results from toxicological and pharmacological studies of the iron(II) coordination complex of the immunoactive dipeptide isoleucyltryptophan (timofer) were presented. It was established that timofer was practically nontoxic and exhibited high immunostimulatory activity when combined with viral and...

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Autores principales: Kholnazarov, B. M., Bunyatyan, N. D., Olefir, Yu. V., Bobizoda, G. M., Prokof’ev, A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089118/
https://www.ncbi.nlm.nih.gov/pubmed/32214539
http://dx.doi.org/10.1007/s11094-017-1632-1
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author Kholnazarov, B. M.
Bunyatyan, N. D.
Olefir, Yu. V.
Bobizoda, G. M.
Prokof’ev, A. B.
author_facet Kholnazarov, B. M.
Bunyatyan, N. D.
Olefir, Yu. V.
Bobizoda, G. M.
Prokof’ev, A. B.
author_sort Kholnazarov, B. M.
collection PubMed
description Results from toxicological and pharmacological studies of the iron(II) coordination complex of the immunoactive dipeptide isoleucyltryptophan (timofer) were presented. It was established that timofer was practically nontoxic and exhibited high immunostimulatory activity when combined with viral and bacterial vaccines.
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spelling pubmed-70891182020-03-23 Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide Kholnazarov, B. M. Bunyatyan, N. D. Olefir, Yu. V. Bobizoda, G. M. Prokof’ev, A. B. Pharm Chem J Article Results from toxicological and pharmacological studies of the iron(II) coordination complex of the immunoactive dipeptide isoleucyltryptophan (timofer) were presented. It was established that timofer was practically nontoxic and exhibited high immunostimulatory activity when combined with viral and bacterial vaccines. Springer US 2017-10-10 2017 /pmc/articles/PMC7089118/ /pubmed/32214539 http://dx.doi.org/10.1007/s11094-017-1632-1 Text en © Springer Science+Business Media, LLC 2017 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Kholnazarov, B. M.
Bunyatyan, N. D.
Olefir, Yu. V.
Bobizoda, G. M.
Prokof’ev, A. B.
Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
title Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
title_full Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
title_fullStr Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
title_full_unstemmed Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
title_short Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
title_sort toxic and immunomodulatory properties of an iron(ii) coordination complex of isoleucyltryptophan dipeptide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089118/
https://www.ncbi.nlm.nih.gov/pubmed/32214539
http://dx.doi.org/10.1007/s11094-017-1632-1
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