Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents

Two series of new aromatic thiosemicarbazone derivatives were synthesized by condensation of N-(4-cyanophenyl)hydrazine carbothioamide (I) and N-(4-methylsulfanylphenyl)hydrazine carbothioamide (II) with appropriate aromatic aldehydes in order to investigate their antiviral and cytostatic potency. T...

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Detalles Bibliográficos
Autores principales: Karaküçük-İyidoğan, A., Aydınöz, B., Taşkın-Tok, T., Oruç-Emre, E. E., Balzarini, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089137/
https://www.ncbi.nlm.nih.gov/pubmed/32214540
http://dx.doi.org/10.1007/s11094-019-01968-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089137/
https://www.ncbi.nlm.nih.gov/pubmed/32214540
http://dx.doi.org/10.1007/s11094-019-01968-3

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