Carbohydrate biomarkers for future disease detection and treatment

Carbohydrates are considered as one of the most important classes of biomarkers for cell types, disease states, protein functions, and developmental states. Carbohydrate “binders” that can specifically recognize a carbohydrate biomarker can be used for developing novel types of site specific deliver...

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Autores principales: Cheng, YunFeng, Li, MinYong, Wang, ShaoRu, Peng, HanJing, Reid, Suazette, Ni, NanTing, Fang, Hao, Xu, WenFang, Wang, BingHe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Science in China Press 2010
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089153/
https://www.ncbi.nlm.nih.gov/pubmed/32214994
http://dx.doi.org/10.1007/s11426-010-0021-3
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author Cheng, YunFeng
Li, MinYong
Wang, ShaoRu
Peng, HanJing
Reid, Suazette
Ni, NanTing
Fang, Hao
Xu, WenFang
Wang, BingHe
author_facet Cheng, YunFeng
Li, MinYong
Wang, ShaoRu
Peng, HanJing
Reid, Suazette
Ni, NanTing
Fang, Hao
Xu, WenFang
Wang, BingHe
author_sort Cheng, YunFeng
collection PubMed
description Carbohydrates are considered as one of the most important classes of biomarkers for cell types, disease states, protein functions, and developmental states. Carbohydrate “binders” that can specifically recognize a carbohydrate biomarker can be used for developing novel types of site specific delivery methods and imaging agents. In this review, we present selected examples of important carbohydrate biomarkers and how they can be targeted for the development of therapeutic and diagnostic agents. Examples are arranged based on disease categories including (1) infectious diseases, (2) cancer, (3) inflammation and immune responses, (4) signal transduction, (5) stem cell transformation, (6) embryo development, and (7) cardiovascular diseases, though some issues cross therapeutic boundaries.
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spelling pubmed-70891532020-03-23 Carbohydrate biomarkers for future disease detection and treatment Cheng, YunFeng Li, MinYong Wang, ShaoRu Peng, HanJing Reid, Suazette Ni, NanTing Fang, Hao Xu, WenFang Wang, BingHe Sci China Chem Reviews Carbohydrates are considered as one of the most important classes of biomarkers for cell types, disease states, protein functions, and developmental states. Carbohydrate “binders” that can specifically recognize a carbohydrate biomarker can be used for developing novel types of site specific delivery methods and imaging agents. In this review, we present selected examples of important carbohydrate biomarkers and how they can be targeted for the development of therapeutic and diagnostic agents. Examples are arranged based on disease categories including (1) infectious diseases, (2) cancer, (3) inflammation and immune responses, (4) signal transduction, (5) stem cell transformation, (6) embryo development, and (7) cardiovascular diseases, though some issues cross therapeutic boundaries. SP Science in China Press 2010-02-07 2010 /pmc/articles/PMC7089153/ /pubmed/32214994 http://dx.doi.org/10.1007/s11426-010-0021-3 Text en © Science in China Press and Springer Berlin Heidelberg 2010 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Reviews
Cheng, YunFeng
Li, MinYong
Wang, ShaoRu
Peng, HanJing
Reid, Suazette
Ni, NanTing
Fang, Hao
Xu, WenFang
Wang, BingHe
Carbohydrate biomarkers for future disease detection and treatment
title Carbohydrate biomarkers for future disease detection and treatment
title_full Carbohydrate biomarkers for future disease detection and treatment
title_fullStr Carbohydrate biomarkers for future disease detection and treatment
title_full_unstemmed Carbohydrate biomarkers for future disease detection and treatment
title_short Carbohydrate biomarkers for future disease detection and treatment
title_sort carbohydrate biomarkers for future disease detection and treatment
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089153/
https://www.ncbi.nlm.nih.gov/pubmed/32214994
http://dx.doi.org/10.1007/s11426-010-0021-3
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