Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein

Rabbit hemorrhagic disease, which is caused by a calicivirus, is a lethal infection of adult animals that is characterized by acute liver damage and disseminated intravascular coagulation. In this study, we report the production of the major structural protein VP60 of rabbit hemorrhagic disease viru...

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Detalles Bibliográficos
Autores principales: Martín-Alonso, José M., Castañón, Sonia, Alonso, Pablo, Parra, Francisco, Ordás, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kluwer Academic Publishers 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089254/
https://www.ncbi.nlm.nih.gov/pubmed/12650532
http://dx.doi.org/10.1023/A:1022112717331
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author Martín-Alonso, José M.
Castañón, Sonia
Alonso, Pablo
Parra, Francisco
Ordás, Ricardo
author_facet Martín-Alonso, José M.
Castañón, Sonia
Alonso, Pablo
Parra, Francisco
Ordás, Ricardo
author_sort Martín-Alonso, José M.
collection PubMed
description Rabbit hemorrhagic disease, which is caused by a calicivirus, is a lethal infection of adult animals that is characterized by acute liver damage and disseminated intravascular coagulation. In this study, we report the production of the major structural protein VP60 of rabbit hemorrhagic disease virus in transgenic tubers of potato plants and its use as an oral immunogen in rabbits.
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spelling pubmed-70892542020-03-23 Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein Martín-Alonso, José M. Castañón, Sonia Alonso, Pablo Parra, Francisco Ordás, Ricardo Transgenic Res Article Rabbit hemorrhagic disease, which is caused by a calicivirus, is a lethal infection of adult animals that is characterized by acute liver damage and disseminated intravascular coagulation. In this study, we report the production of the major structural protein VP60 of rabbit hemorrhagic disease virus in transgenic tubers of potato plants and its use as an oral immunogen in rabbits. Kluwer Academic Publishers 2003 /pmc/articles/PMC7089254/ /pubmed/12650532 http://dx.doi.org/10.1023/A:1022112717331 Text en © Kluwer Academic Publishers 2003 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Martín-Alonso, José M.
Castañón, Sonia
Alonso, Pablo
Parra, Francisco
Ordás, Ricardo
Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein
title Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein
title_full Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein
title_fullStr Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein
title_full_unstemmed Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein
title_short Oral Immunization using Tuber Extracts from Transgenic Potato Plants Expressing Rabbit Hemorrhagic Disease Virus Capsid Protein
title_sort oral immunization using tuber extracts from transgenic potato plants expressing rabbit hemorrhagic disease virus capsid protein
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089254/
https://www.ncbi.nlm.nih.gov/pubmed/12650532
http://dx.doi.org/10.1023/A:1022112717331
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