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Middle East respiratory syndrome coronavirus: a comprehensive review

The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be...

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Detalles Bibliográficos
Autores principales: Shehata, Mahmoud M., Gomaa, Mokhtar R., Ali, Mohamed A., Kayali, Ghazi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089261/
https://www.ncbi.nlm.nih.gov/pubmed/26791756
http://dx.doi.org/10.1007/s11684-016-0430-6
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author Shehata, Mahmoud M.
Gomaa, Mokhtar R.
Ali, Mohamed A.
Kayali, Ghazi
author_facet Shehata, Mahmoud M.
Gomaa, Mokhtar R.
Ali, Mohamed A.
Kayali, Ghazi
author_sort Shehata, Mahmoud M.
collection PubMed
description The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it.
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spelling pubmed-70892612020-03-23 Middle East respiratory syndrome coronavirus: a comprehensive review Shehata, Mahmoud M. Gomaa, Mokhtar R. Ali, Mohamed A. Kayali, Ghazi Front Med Review The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it. Higher Education Press 2016-01-20 2016 /pmc/articles/PMC7089261/ /pubmed/26791756 http://dx.doi.org/10.1007/s11684-016-0430-6 Text en © Higher Education Press and Springer-Verlag Berlin Heidelberg 2016 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Shehata, Mahmoud M.
Gomaa, Mokhtar R.
Ali, Mohamed A.
Kayali, Ghazi
Middle East respiratory syndrome coronavirus: a comprehensive review
title Middle East respiratory syndrome coronavirus: a comprehensive review
title_full Middle East respiratory syndrome coronavirus: a comprehensive review
title_fullStr Middle East respiratory syndrome coronavirus: a comprehensive review
title_full_unstemmed Middle East respiratory syndrome coronavirus: a comprehensive review
title_short Middle East respiratory syndrome coronavirus: a comprehensive review
title_sort middle east respiratory syndrome coronavirus: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089261/
https://www.ncbi.nlm.nih.gov/pubmed/26791756
http://dx.doi.org/10.1007/s11684-016-0430-6
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