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Complex positive selection pressures drive the evolution of HIV-1 with different co-receptor tropisms
HIV-1 co-receptor tropism is central for understanding the transmission and pathogenesis of HIV-1 infection. We performed a genome-wide comparison between the adaptive evolution of R5 and X4 variants from HIV-1 subtypes B and C. The results showed that R5 and X4 variants experienced differential evo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Science China Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089306/ https://www.ncbi.nlm.nih.gov/pubmed/20953943 http://dx.doi.org/10.1007/s11427-010-4066-5 |