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A rational approach to selective pharmacophore designing: an innovative strategy for specific recognition of Gsk3β
We propose a novel cheminformatics approach that combines structure and ligand-based design to identify target-specific pharmacophores with well-defined exclusion ability. Our strategy includes the prediction of selective interactions, developing structure, and knowledge-based selective pharmacophor...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089308/ https://www.ncbi.nlm.nih.gov/pubmed/22918724 http://dx.doi.org/10.1007/s11030-012-9387-9 |