Advanced case of PKDL due to delayed treatment: A rare case report

Post-kala-azar dermal leishmaniasis (PKDL) is clinical outcome of visceral leishmaniasis (VL) and is thought to be the potential reservoir of parasite. Miltefosine (MF) is the only oral drug existing for treatment of post-kala-azar dermal leishmaniasis (PKDL). Increased miltefosine tolerance in clin...

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Detalles Bibliográficos
Autores principales: Topno, Roshan Kamal, Rabi Das, Vidya Nand, Kumar, Maneesh, Madhukar, Major, Pandey, Krishna, Verma, Neena, Agrawal, Kanhaiya, Lal, Chandra Shekhar, Siddiqui, Niyamat Ali, Bimal, Sanjiva, Das, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Symposium
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089400/
https://www.ncbi.nlm.nih.gov/pubmed/32203500
http://dx.doi.org/10.1371/journal.pntd.0008052
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author Topno, Roshan Kamal
Rabi Das, Vidya Nand
Kumar, Maneesh
Madhukar, Major
Pandey, Krishna
Verma, Neena
Agrawal, Kanhaiya
Lal, Chandra Shekhar
Siddiqui, Niyamat Ali
Bimal, Sanjiva
Das, Pradeep
author_facet Topno, Roshan Kamal
Rabi Das, Vidya Nand
Kumar, Maneesh
Madhukar, Major
Pandey, Krishna
Verma, Neena
Agrawal, Kanhaiya
Lal, Chandra Shekhar
Siddiqui, Niyamat Ali
Bimal, Sanjiva
Das, Pradeep
author_sort Topno, Roshan Kamal
collection PubMed
description Post-kala-azar dermal leishmaniasis (PKDL) is clinical outcome of visceral leishmaniasis (VL) and is thought to be the potential reservoir of parasite. Miltefosine (MF) is the only oral drug existing for treatment of post-kala-azar dermal leishmaniasis (PKDL). Increased miltefosine tolerance in clinical isolates of Leishmania donovani has been reported and is one of the major concerns in the treatment of PKDL. Here, we report a highly ulcerated PKDL case that was successfully cured after miltefosine treatment.
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spelling pubmed-70894002020-04-01 Advanced case of PKDL due to delayed treatment: A rare case report Topno, Roshan Kamal Rabi Das, Vidya Nand Kumar, Maneesh Madhukar, Major Pandey, Krishna Verma, Neena Agrawal, Kanhaiya Lal, Chandra Shekhar Siddiqui, Niyamat Ali Bimal, Sanjiva Das, Pradeep PLoS Negl Trop Dis Symposium Post-kala-azar dermal leishmaniasis (PKDL) is clinical outcome of visceral leishmaniasis (VL) and is thought to be the potential reservoir of parasite. Miltefosine (MF) is the only oral drug existing for treatment of post-kala-azar dermal leishmaniasis (PKDL). Increased miltefosine tolerance in clinical isolates of Leishmania donovani has been reported and is one of the major concerns in the treatment of PKDL. Here, we report a highly ulcerated PKDL case that was successfully cured after miltefosine treatment. Public Library of Science 2020-03-23 /pmc/articles/PMC7089400/ /pubmed/32203500 http://dx.doi.org/10.1371/journal.pntd.0008052 Text en © 2020 Topno et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Symposium
Topno, Roshan Kamal
Rabi Das, Vidya Nand
Kumar, Maneesh
Madhukar, Major
Pandey, Krishna
Verma, Neena
Agrawal, Kanhaiya
Lal, Chandra Shekhar
Siddiqui, Niyamat Ali
Bimal, Sanjiva
Das, Pradeep
Advanced case of PKDL due to delayed treatment: A rare case report
title Advanced case of PKDL due to delayed treatment: A rare case report
title_full Advanced case of PKDL due to delayed treatment: A rare case report
title_fullStr Advanced case of PKDL due to delayed treatment: A rare case report
title_full_unstemmed Advanced case of PKDL due to delayed treatment: A rare case report
title_short Advanced case of PKDL due to delayed treatment: A rare case report
title_sort advanced case of pkdl due to delayed treatment: a rare case report
topic Symposium
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089400/
https://www.ncbi.nlm.nih.gov/pubmed/32203500
http://dx.doi.org/10.1371/journal.pntd.0008052
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