Cargando…

Genome-Wide Association Studies Complemented with Mechanistic Biological Studies Identify Sortilin 1 as a Novel Regulator of Cholesterol Trafficking

Detalles Bibliográficos
Autor principal:	Marian, Ali J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Current Science Inc. 2011
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089479/ https://www.ncbi.nlm.nih.gov/pubmed/21287300 http://dx.doi.org/10.1007/s11883-011-0168-1

Ejemplares similares

Regulation of lysosomal trafficking of progranulin by sortilin and prosaposin
por: Du, Huan, et al.
Publicado: (2022)

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
por: Zhou, Xiaolai, et al.
Publicado: (2015)

Dimerization of sortilin regulates its trafficking to extracellular vesicles
por: Itoh, Shinsuke, et al.
Publicado: (2018)

TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin
por: Yabe-Wada, Toshiki, et al.
Publicado: (2016)

Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin
por: Venkat, Swati, et al.
Publicado: (2017)

A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9
por: Zeitlinger, Markus, et al.
Publicado: (2021)

Editorial: Sortilin and Sortilin Partners in Physiology and Pathologies
por: Mazella, Jean, et al.
Publicado: (2019)

Identifying patterns of kinesiophobia trajectories among COPD patients: A longitudinal study
por: Liang, Facun, et al.
Publicado: (2023)

C-Terminus of Progranulin Interacts with the Beta-Propeller Region of Sortilin to Regulate Progranulin Trafficking
por: Zheng, Yanqiu, et al.
Publicado: (2011)

Sortilin and atherosclerosis
por: Mortensen, Martin B., et al.
Publicado: (2015)

Return of individual genomic research results within the PRAEGNANT multicenter registry study
por: Huebner, Hanna, et al.
Publicado: (2022)

Novel Extranasal Tear Stimulation: Pivotal Study Results
por: Ji, Marco H., et al.
Publicado: (2020)

Pegcetacoplan controls hemolysis in complement inhibitor–naive patients with paroxysmal nocturnal hemoglobinuria
por: Wong, Raymond Siu Ming, et al.
Publicado: (2023)

Mammographic screening detects low-risk tumor biology breast cancers
por: Drukker, C. A., et al.
Publicado: (2014)

Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin
por: Hagita, Sumihiko, et al.
Publicado: (2018)

C1-inhibitor treatment in patients with severe complement-mediated autoimmune hemolytic anemia
por: de Boer, Esther C. W., et al.
Publicado: (2023)

The sensitivity and specificity of methylene blue spray to identify the parathyroid gland during thyroidectomy
por: Piromchai, Patorn, et al.
Publicado: (2019)

The Intracellular Domain of Sortilin Interacts with Amyloid Precursor Protein and Regulates Its Lysosomal and Lipid Raft Trafficking
por: Yang, Miao, et al.
Publicado: (2013)

Identifying and treating resistant hypertension in PRECISION: A randomized long‐term clinical trial with aprocitentan
por: Danaietash, Parisa, et al.
Publicado: (2022)

Vascular surgery patients with elevated neutrophil-to-lymphocyte ratios have downregulated neutrophil complement RNA expression
por: Chan, Ernest R., et al.
Publicado: (2022)

A comparison between young and old patients with triple-negative breast cancer: biology, survival and metastatic patterns
por: Tzikas, Anna-Karin, et al.
Publicado: (2020)

An observational study on the adherence to study registrations in German interventional and observational studies from various fields
por: Thiele, Christian, et al.
Publicado: (2023)

Genome-wide methylation profiling of early colorectal cancer using an Illumina Infinium Methylation EPIC BeadChip
por: Wu, Yu-Ling, et al.
Publicado: (2022)

The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study
por: Elshafei, Mohamed Nabil, et al.
Publicado: (2022)

A phase III study of the efficacy and safety of a novel iron-based phosphate binder in dialysis patients
por: Floege, Jürgen, et al.
Publicado: (2014)

2304: Identifying optimal multiple sclerosis (MS)-specific atrophy markers as primary endpoint for Phase II s in progressive MS
por: Azevedo, Christina, et al.
Publicado: (2018)

Adrenomedullin for biologic‐resistant Crohn's disease: A randomized, double‐blind, placebo‐controlled phase 2a clinical trial
por: Kita, Toshihiro, et al.
Publicado: (2022)

2165: Effects of a novel 2-phase rehabilitation program on postural control in older adults: A pilot study
por: Papa, Evan, et al.
Publicado: (2018)

Evidence that the Plasmodium falciparum Protein Sortilin Potentially Acts as an Escorter for the Trafficking of the Rhoptry-Associated Membrane Antigen to the Rhoptries
por: Hallée, Stéphanie, et al.
Publicado: (2018)

Gut microbiota‐derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID‐19: An open‐label pilot study
por: Zhang, Lin, et al.
Publicado: (2022)

Pro-neurotrophins, sortilin, and nociception
por: Lewin, Gary R, et al.
Publicado: (2014)

A prospective observational study of patient-reported functioning and quality of life in advanced and metastatic breast cancer utilizing a novel mobile application
por: Richardson, David, et al.
Publicado: (2021)

Evaluation of heart rate measurements in clinical studies: a prospective cohort study in patients with heart disease
por: Albanese, Marco, et al.
Publicado: (2016)

A mixed methods study protocol to identify research priorities for perioperative medicine in Australia
por: Wallace, Sophie K.A., et al.
Publicado: (2023)

Anti-sortilin1 Antibody Up-Regulates Progranulin via Sortilin1 Down-Regulation
por: Miyakawa, Shuuichi, et al.
Publicado: (2020)

A highly sensitive biosensor based on Au NPs/rGO-PAMAM-Fc nanomaterials for detection of cholesterol
por: Zhu, Jianmeng, et al.
Publicado: (2019)

Evaluation of applying IHC4 as a prognostic model in the translational study of Intergroup Exemestane Study (IES): PathIES
por: Cheang, M. C. U., et al.
Publicado: (2017)

IPET study: an FLT-PET window study to assess the activity of the steroid sulfatase inhibitor irosustat in early breast cancer
por: Palmieri, Carlo, et al.
Publicado: (2017)

Improved participants’ understanding in a healthy volunteer study using the SIDCER informed consent form: a randomized-controlled study
por: Koonrungsesomboon, Nut, et al.
Publicado: (2015)

Response and Adherence to Nilotinib in Daily practice (RAND study): an in-depth observational study of chronic myeloid leukemia patients treated with nilotinib
por: Boons, Christel C. L. M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1s3oa6dhoipgh0l7kin9iml7vn