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Contribution of Leishmania braziliensis antigen-specific CD4(+) T, CD8(+) T, NK and CD3(+)CD56(+)NKT cells in the immunopathogenesis of cutaneous leishmaniasis patients: Cytotoxic, activation and exhaustion profiles
The pathogenesis of cutaneous leishmaniasis (CL) caused by Leishmania (Viannia) braziliensis is dictated mainly by the immune-mediated-tissue inflammation developed. The understanding of the immunological mechanisms that generate tissue damage or resolution of lesions is the key to the development o...
Autores principales: | Cunha, Clarissa F., Ferraz-Nogueira, Raquel, Costa, Vanessa F. A., Pimentel, Maria Inês F., Chometon, Thaize Q., Lyra, Marcelo R., Schubach, Armando O., Da-Cruz, Alda Maria, Bertho, Alvaro Luiz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089553/ https://www.ncbi.nlm.nih.gov/pubmed/32203546 http://dx.doi.org/10.1371/journal.pone.0229400 |
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