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Function of PIN1 in Cancer Development and Its Inhibitors as Cancer Therapeutics

Peptidyl-prolyl isomerase (PIN1) specifically binds and isomerizes the phosphorylated serine/threonine–proline (pSer/Thr–Pro) motif, which results in the alteration of protein structure, function, and stability. The altered structure and function of these phosphorylated proteins regulated by PIN1 ar...

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Detalles Bibliográficos
Autores principales: Yu, Ji Hoon, Im, Chun Young, Min, Sang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089927/
https://www.ncbi.nlm.nih.gov/pubmed/32258027
http://dx.doi.org/10.3389/fcell.2020.00120