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Function of PIN1 in Cancer Development and Its Inhibitors as Cancer Therapeutics
Peptidyl-prolyl isomerase (PIN1) specifically binds and isomerizes the phosphorylated serine/threonine–proline (pSer/Thr–Pro) motif, which results in the alteration of protein structure, function, and stability. The altered structure and function of these phosphorylated proteins regulated by PIN1 ar...
Autores principales: | Yu, Ji Hoon, Im, Chun Young, Min, Sang-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089927/ https://www.ncbi.nlm.nih.gov/pubmed/32258027 http://dx.doi.org/10.3389/fcell.2020.00120 |
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