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Haplotype-Based Analysis of KIR-Gene Profiles in a South European Population—Distribution of Standard and Variant Haplotypes, and Identification of Novel Recombinant Structures
Inhibitory Killer-cell Immunoglobulin-like Receptors (KIR) specific for HLA class I molecules enable human natural killer cells to monitor altered antigen presentation in pathogen-infected and tumor cells. KIR genes display extensive copy-number variation and allelic polymorphism. They organize in a...
Autores principales: | Cisneros, Elisa, Moraru, Manuela, Gómez-Lozano, Natalia, Muntasell, Aura, López-Botet, Miguel, Vilches, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089957/ https://www.ncbi.nlm.nih.gov/pubmed/32256494 http://dx.doi.org/10.3389/fimmu.2020.00440 |
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