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Low-dose 17α-ethinyl estradiol (EE) exposure exacerbates lupus renal disease and modulates immune responses to TLR7/9 agonists in genetically autoimmune-prone mice

Estrogens have been shown to regulate the immune system and modulate multiple autoimmune diseases. 17α-ethinyl estradiol (EE), a synthetic analog of 17β-estradiol, is prescribed commonly and found in oral contraceptives and hormone replacement therapies. Surprisingly, few studies have investigated t...

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Detalles Bibliográficos
Autores principales:	Edwards, Michael R., Dai, Rujuan, Heid, Bettina, Cowan, Catharine, Werre, Stephen R., Cecere, Thomas, Ahmed, S. Ansar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090002/ https://www.ncbi.nlm.nih.gov/pubmed/32251357 http://dx.doi.org/10.1038/s41598-020-62124-6

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