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Genome-Wide DNA Methylation Enhances Stemness in the Mechanical Selection of Tumor-Repopulating Cells

BACKGROUND: DNA methylation plays essential roles in tumor occurrence and stemness maintenance. Tumor-repopulating cells (TRCs) are cancer stem cell (CSC)-like cells with highly tumorigenic and self-renewing abilities, which were selected from tumor cells in soft three-dimensional (3D) fibrin gels....

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Detalles Bibliográficos
Autores principales:	Huang, Wei, Hu, Hui, Zhang, Qiong, Wang, Ning, Yang, Xiangliang, Guo, An-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090028/ https://www.ncbi.nlm.nih.gov/pubmed/32258002 http://dx.doi.org/10.3389/fbioe.2020.00088

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