CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation

Chromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers. The mechanism, however, is only partially resolved, and it is unclear if it is conserved among the four remodeller families. Here we use single-molecule assays to examine the mechanism of action of CHD4, which is p...

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Detalles Bibliográficos
Autores principales: Zhong, Yichen, Paudel, Bishnu P., Ryan, Daniel P., Low, Jason K. K., Franck, Charlotte, Patel, Karishma, Bedward, Max J., Torrado, Mario, Payne, Richard J., van Oijen, Antoine M., Mackay, Joel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090039/
https://www.ncbi.nlm.nih.gov/pubmed/32251276
http://dx.doi.org/10.1038/s41467-020-15183-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090039/
https://www.ncbi.nlm.nih.gov/pubmed/32251276
http://dx.doi.org/10.1038/s41467-020-15183-2

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