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Developing a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps

Hydroxytyrosol is an antioxidant free radical scavenger that is biosynthesized from tyrosine. In metabolic engineering efforts, the use of the mouse tyrosine hydroxylase limits its production. Here, we design an efficient whole-cell catalyst of hydroxytyrosol in Escherichia coli by de-bottlenecking...

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Detalles Bibliográficos
Autores principales:	Yao, Jun, He, Yang, Su, Nannan, Bharath, Sakshibeedu R., Tao, Yong, Jin, Jian-Ming, Chen, Wei, Song, Haiwei, Tang, Shuang-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090077/ https://www.ncbi.nlm.nih.gov/pubmed/32251291 http://dx.doi.org/10.1038/s41467-020-14918-5

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