Cofilin dysregulation alters actin turnover in frataxin-deficient neurons

Abnormalities in actin cytoskeleton have been linked to Friedreich’s ataxia (FRDA), an inherited peripheral neuropathy characterised by an early loss of neurons in dorsal root ganglia (DRG) among other clinical symptoms. Despite all efforts to date, we still do not fully understand the molecular eve...

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Detalles Bibliográficos
Autores principales: Muñoz-Lasso, Diana C., Mollá, Belén, Calap-Quintana, Pablo, García-Giménez, José Luis, Pallardo, Federico V., Palau, Francesc, Gonzalez-Cabo, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090085/
https://www.ncbi.nlm.nih.gov/pubmed/32251310
http://dx.doi.org/10.1038/s41598-020-62050-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090085/
https://www.ncbi.nlm.nih.gov/pubmed/32251310
http://dx.doi.org/10.1038/s41598-020-62050-7

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