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Cofilin dysregulation alters actin turnover in frataxin-deficient neurons
Abnormalities in actin cytoskeleton have been linked to Friedreich’s ataxia (FRDA), an inherited peripheral neuropathy characterised by an early loss of neurons in dorsal root ganglia (DRG) among other clinical symptoms. Despite all efforts to date, we still do not fully understand the molecular eve...
Autores principales: | Muñoz-Lasso, Diana C., Mollá, Belén, Calap-Quintana, Pablo, García-Giménez, José Luis, Pallardo, Federico V., Palau, Francesc, Gonzalez-Cabo, Pilar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090085/ https://www.ncbi.nlm.nih.gov/pubmed/32251310 http://dx.doi.org/10.1038/s41598-020-62050-7 |
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