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Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient

Mucormycosis is an uncommon and acute fungal infection, with high morbidity and mortality. Traumatic mucormycosis mainly occurs in military conflicts, civilian trauma, and vehicle accidents. Hurricanes, tornadoes, floods, and tsunamis also play a major role in causing mucormycosis by inoculation. He...

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Autores principales: Meidani, Mohsen, Abtahi, Sayed Hamidreza, Mohammadi, Rasoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090215/
https://www.ncbi.nlm.nih.gov/pubmed/32256124
http://dx.doi.org/10.2147/IMCRJ.S246072
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author Meidani, Mohsen
Abtahi, Sayed Hamidreza
Mohammadi, Rasoul
author_facet Meidani, Mohsen
Abtahi, Sayed Hamidreza
Mohammadi, Rasoul
author_sort Meidani, Mohsen
collection PubMed
description Mucormycosis is an uncommon and acute fungal infection, with high morbidity and mortality. Traumatic mucormycosis mainly occurs in military conflicts, civilian trauma, and vehicle accidents. Hurricanes, tornadoes, floods, and tsunamis also play a major role in causing mucormycosis by inoculation. Herein, we presented a case of trauma-related mucormycosis in a 70-year-old diabetic male. He referred to a specialty clinic due to the auricular swelling after having fallen and having a major trauma in his ear. Pathologic examination of necrotic cartilage revealed broad ribbon like aseptate hyphae. Antifungal therapy with amphotericin B deoxycholate (1.5 mg/kg/day) was administered for 6 weeks as an initial therapy, and the patient was discharged with a regimen of posaconazole oral solution (400 mg PO bid with meals) for 8 weeks. He followed up for one year and there was no recurrence of the infection. In conclusion, traumatic mucormycosis is a rare but potentially life-threatening fungal infection. Early diagnosis and surgical excision are essential regarding the management of this critical condition. Knowing the underlying diseases is preferable to early diagnosis and timely initiation of antifungal therapy in order to improve survival rates.
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spelling pubmed-70902152020-04-01 Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient Meidani, Mohsen Abtahi, Sayed Hamidreza Mohammadi, Rasoul Int Med Case Rep J Case Report Mucormycosis is an uncommon and acute fungal infection, with high morbidity and mortality. Traumatic mucormycosis mainly occurs in military conflicts, civilian trauma, and vehicle accidents. Hurricanes, tornadoes, floods, and tsunamis also play a major role in causing mucormycosis by inoculation. Herein, we presented a case of trauma-related mucormycosis in a 70-year-old diabetic male. He referred to a specialty clinic due to the auricular swelling after having fallen and having a major trauma in his ear. Pathologic examination of necrotic cartilage revealed broad ribbon like aseptate hyphae. Antifungal therapy with amphotericin B deoxycholate (1.5 mg/kg/day) was administered for 6 weeks as an initial therapy, and the patient was discharged with a regimen of posaconazole oral solution (400 mg PO bid with meals) for 8 weeks. He followed up for one year and there was no recurrence of the infection. In conclusion, traumatic mucormycosis is a rare but potentially life-threatening fungal infection. Early diagnosis and surgical excision are essential regarding the management of this critical condition. Knowing the underlying diseases is preferable to early diagnosis and timely initiation of antifungal therapy in order to improve survival rates. Dove 2020-03-18 /pmc/articles/PMC7090215/ /pubmed/32256124 http://dx.doi.org/10.2147/IMCRJ.S246072 Text en © 2020 Meidani et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Meidani, Mohsen
Abtahi, Sayed Hamidreza
Mohammadi, Rasoul
Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient
title Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient
title_full Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient
title_fullStr Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient
title_full_unstemmed Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient
title_short Traumatic Mucormycosis of Auricular Cartilage in an Iranian Diabetic Patient
title_sort traumatic mucormycosis of auricular cartilage in an iranian diabetic patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090215/
https://www.ncbi.nlm.nih.gov/pubmed/32256124
http://dx.doi.org/10.2147/IMCRJ.S246072
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