Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However, the delivery of naked siRNAs is challenging becaus...

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Detalles Bibliográficos
Autores principales: Kim, Taejin, Viard, Mathias, Afonin, Kirill A., Gupta, Kshitij, Popov, Mary, Salotti, Jacqueline, Johnson, Peter F., Linder, Charles, Heldman, Eliahu, Shapiro, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090283/
https://www.ncbi.nlm.nih.gov/pubmed/32200271
http://dx.doi.org/10.1016/j.omtn.2020.02.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090283/
https://www.ncbi.nlm.nih.gov/pubmed/32200271
http://dx.doi.org/10.1016/j.omtn.2020.02.011

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