Cargando…

Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). However, the delivery of naked siRNAs is challenging becaus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Taejin, Viard, Mathias, Afonin, Kirill A., Gupta, Kshitij, Popov, Mary, Salotti, Jacqueline, Johnson, Peter F., Linder, Charles, Heldman, Eliahu, Shapiro, Bruce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090283/ https://www.ncbi.nlm.nih.gov/pubmed/32200271 http://dx.doi.org/10.1016/j.omtn.2020.02.011

Ejemplares similares

In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery
por: Kim, Taejin, et al.
Publicado: (2013)

Steric environment around acetylcholine head groups of bolaamphiphilic nanovesicles influences the release rate of encapsulated compounds
por: Stern, Avital, et al.
Publicado: (2014)

Structure-Based Design of Dendritic Peptide Bolaamphiphiles for siRNA Delivery
por: Zeng, Hanxiang, et al.
Publicado: (2015)

Functionalized non-viral cationic vectors for effective siRNA induced cancer therapy
por: Gupta, Kshitij, et al.
Publicado: (2017)

Activation of different split functionalities upon re-association of RNA-DNA hybrids
por: Afonin, Kirill A., et al.
Publicado: (2013)

Reduction-Responsive Cationic Vesicles from Bolaamphiphiles with Ionizable Amino Acid or Dipeptide Polar Heads
por: Bernal-Martínez, Ana M., et al.
Publicado: (2023)

Biomedically Relevant Applications of Bolaamphiphiles and Bolaamphiphile-Containing Materials
por: Hughes, Jake R., et al.
Publicado: (2021)

Amylose-Based Cationic Star Polymers for siRNA Delivery
por: Nishimura, Tomoki, et al.
Publicado: (2015)

Triggering RNAi with multifunctional RNA nanoparticles and their delivery
por: Dao, Bich Ngoc, et al.
Publicado: (2015)

Multifunctional RNA Nanoparticles
por: Afonin, Kirill A., et al.
Publicado: (2014)

Cationic Amphiphilic Bolaamphiphile-based Delivery of Antisense Oligonucleotides Provides a Potentially Microbiome Sparing Treatment for C. difficile
por: Sharma, Arun K., et al.
Publicado: (2018)

The siRNAsome: A Cation‐Free and Versatile Nanostructure for siRNA and Drug Co‐delivery
por: Zheng, Meng, et al.
Publicado: (2019)

Planar-bilayer activities of linear oligoester bolaamphiphiles
por: Chui, Jonathan K W, et al.
Publicado: (2011)

In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes
por: Shrivats, Arun R., et al.
Publicado: (2015)

Cationic Magnetite Nanoparticles for Increasing siRNA Hybridization Rates
por: Prilepskii, Artur Y., et al.
Publicado: (2020)

A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery
por: Lu, James J., et al.
Publicado: (2009)

Cationic micelle-based siRNA delivery for efficient colon cancer gene therapy
por: Lu, Yongping, et al.
Publicado: (2019)

Polythiophenes with Cationic Phosphonium Groups as Vectors for Imaging, siRNA Delivery, and Photodynamic Therapy
por: Lichon, Laure, et al.
Publicado: (2020)

Skin Delivery of siRNA Using Sponge Spicules in Combination with Cationic Flexible Liposomes
por: Liang, XueJiao, et al.
Publicado: (2020)

Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery
por: Yu, Xiaolin, et al.
Publicado: (2021)

In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles
por: Afonin, Kirill A., et al.
Publicado: (2014)

Effect of the amount of cationic lipid used to complex siRNA on the cytotoxicity and proinflammatory activity of siRNA-solid lipid nanoparticles
por: Hanafy, Mahmoud S., et al.
Publicado: (2023)

Edible and cation-free kiwi fruit derived vesicles mediated EGFR-targeted siRNA delivery to inhibit multidrug resistant lung cancer
por: Huang, Haoying, et al.
Publicado: (2023)

Carbamate-Based Bolaamphiphile as Low-Molecular-Weight Hydrogelators
por: Latxague, Laurent, et al.
Publicado: (2016)

Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery
por: Nadithe, Venkatareddy, et al.
Publicado: (2014)

Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro
por: Yang, Wenqian, et al.
Publicado: (2021)

Tuning the cationic interface of simple polydiacetylene micelles to improve siRNA delivery at the cellular level
por: Hoang, Minh-Duc, et al.
Publicado: (2019)

Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006)

Dendrimers for siRNA Delivery
por: Biswas, Swati, et al.
Publicado: (2013)

Bolaamphiphilic properties and pH-dependent micellization of quercetin polyglycoside
por: Nargis, Mahmuda, et al.
Publicado: (2019)

Bolaamphiphilic Bis-Dehydropeptide Hydrogels as Potential Drug Release Systems
por: Amorim, Carolina, et al.
Publicado: (2021)

Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells
por: Białkowska, Kamila, et al.
Publicado: (2021)

Treatment of Ulcerative Colitis by Cationic Liposome Delivered NLRP3 siRNA
por: Huang, Jing, et al.
Publicado: (2023)

pH-Sensitive carboxymethyl chitosan-modified cationic liposomes for sorafenib and siRNA co-delivery
por: Yao, Yao, et al.
Publicado: (2015)

siRNA delivery targeting to the lung via agglutination-induced accumulation and clearance of cationic tetraamino fullerene
por: MINAMI, Kosuke, et al.
Publicado: (2014)

Lyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery
por: Ngamcherdtrakul, Worapol, et al.
Publicado: (2018)

In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles
por: Kaps, Leonard, et al.
Publicado: (2020)

Design and In Vitro Evaluation of Novel Cationic Lipids for siRNA Delivery in Breast Cancer Cell Lines
por: Vaidya, Sandeep, et al.
Publicado: (2022)

Synthesis of siRNAs incorporated with cationic peptides R8G7 and R8A7 and the effect of the modifications on siRNA properties
por: Matsubara, Miho, et al.
Publicado: (2020)

Carbon Nanotubes: Solution for the Therapeutic Delivery of siRNA?
por: Kirkpatrick, D. Lynn, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_kaqch34aul83g4kij9v9jlqnsm