Cargando…
Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas
BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing efforts to develop new drugs with improved effectiveness for this disease. BI...
Autores principales: | Kim, Jean, Oh, Ju Hun, Harlem, Heather, Culler, Michael D., Ku, Cheol Ryong, Lee, Eun Jig |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Endocrine Society
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090307/ https://www.ncbi.nlm.nih.gov/pubmed/32207278 http://dx.doi.org/10.3803/EnM.2020.35.1.177 |
Ejemplares similares
-
OR06-02 TBR-760, a Chimeric Somatostatin-Dopamine Compound, Arrests Aggressive Non-Functioning Pituitary Adenoma Growth In Vivo
por: Halem, Heather A, et al.
Publicado: (2020) -
Associations of GNAS Mutations with Surgical Outcomes in Patients with Growth Hormone-Secreting Pituitary Adenoma
por: Jung, Hyein, et al.
Publicado: (2021) -
Clinical applications of somatostatin analogs for growth hormone-secreting pituitary adenomas
por: Wang, Ji-wen, et al.
Publicado: (2014) -
Somatostatin-Dopamine Chimeric Molecules in Neuroendocrine Neoplasms
por: Cantone, Maria Celeste, et al.
Publicado: (2021) -
TBR-760, a Dopamine-Somatostatin Compound, Arrests Growth of Aggressive Nonfunctioning Pituitary Adenomas in Mice
por: Halem, Heather A, et al.
Publicado: (2020)