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Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation
The pathophysiology of type 2 diabetes mellitus (T2DM) is characterized by not only insulin resistance, but also the abnormal regulation of glucagon secretion, suggesting that antagonizing the glucagon-induced signaling pathway has therapeutic potential in the treatment of T2DM. Although various Kam...
Autores principales: | Funakoshi-Tago, Megumi, Yu, Seisho, Kushida, Akira, Takeuchi, Kazusane, Tamura, Hiroomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090351/ https://www.ncbi.nlm.nih.gov/pubmed/32215330 http://dx.doi.org/10.1016/j.heliyon.2020.e03598 |
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