Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos

In mitochondria, the carrier translocase (TIM22 complex) facilitates membrane insertion of multi-spanning proteins with internal targeting signals into the inner membrane [1, 2, 3]. Tom70, a subunit of TOM complex, represents the major receptor for these precursors [2, 4, 5, 6]. After transport acro...

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Detalles Bibliográficos
Autores principales: Gomkale, Ridhima, Cruz-Zaragoza, Luis Daniel, Suppanz, Ida, Guiard, Bernard, Montoya, Julio, Callegari, Sylvie, Pacheu-Grau, David, Warscheid, Bettina, Rehling, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090383/
https://www.ncbi.nlm.nih.gov/pubmed/32142709
http://dx.doi.org/10.1016/j.cub.2020.01.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7090383/
https://www.ncbi.nlm.nih.gov/pubmed/32142709
http://dx.doi.org/10.1016/j.cub.2020.01.024

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